Genetic Analysis Workshop 18: Methods and strategies for analyzing human sequence and phenotype data in members of extended pedigrees

Details

• Alternative Title:
  BMC Proc
• Personal Author:
  Bickeböller, Heike ; Bailey, Julia N ; Beyene, Joseph ; Cantor, Rita M ; Cordell, Heather J ; Culverhouse, Robert C ; Engelman, Corinne D ; Fardo, David W ; Ghosh, Saurabh ; König, Inke R ; Lorenzo Bermejo, Justo ; Melton, Phillip E ; Santorico, Stephanie A ; Satten, Glen A ; Sun, Lei ; Tintle, Nathan L ; Ziegler, Andreas ; MacCluer, Jean W ; Almasy, Laura
• Description:
  Genetic Analysis Workshop 18 provided a platform for developing and evaluating statistical methods to analyze whole-genome sequence data from a pedigree-based sample. In this article we present an overview of the data sets and the contributions that analyzed these data. The family data, donated by the Type 2 Diabetes Genetic Exploration by Next-Generation Sequencing in Ethnic Samples Consortium, included sequence-level genotypes based on sequencing and imputation, genome-wide association genotypes from prior genotyping arrays, and phenotypes from longitudinal assessments. The contributions from individual research groups were extensively discussed before, during, and after the workshop in theme-based discussion groups before being submitted for publication.
• Subjects:
  Proceedings
• Source:
  BMC Proc. 2014; 8(Suppl 1):S1.
• Document Type:
  Journal Article
• Volume:
  8
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:0730acfede7f4a410c0ae916a592bafb3685c00c7fe83d39561ac7fd7bac8c88fd9fdca61ec0db52f60712b0552d0d392aa2cb54f1a09078fbf6ff8f08f79943
• Download URL:
  https://stacks.cdc.gov/view/cdc/24865/cdc_24865_DS1.pdf
• File Type:
  [PDF - 198.56 KB ]