Association of respiratory symptoms with body mass index and occupational exposure comparing sexes and subjects with and without asthma: follow-up of a Norwegian population study (the Telemark study).

Details

• Personal Author:
  Brunborg C ; Fell AKM ; Henneberger, Paul K. ; Klepaker G ; Kongerud J ; Torén, Kjell
• Description:
  BACKGROUND: Occupational exposure and increased body mass index (BMI) are associated with respiratory symptoms. This study investigated whether the association of a respiratory burden score with changes in BMI as well as changes in occupational exposure to vapours, gas, dust and fumes (VGDF) varied in subjects with and without asthma and in both sexes over a 5-year period. METHODS: In a 5-year follow-up of a population-based study, 6350 subjects completed a postal questionnaire in 2013 and 2018. A respiratory burden score based on self-reported respiratory symptoms, BMI and frequency of occupational exposure to VGDF were calculated at both times. The association between change in respiratory burden score and change in BMI or VGDF exposure was assessed using stratified regression models. RESULTS: Changes in respiratory burden score and BMI were associated with a beta-coefficient of 0.05 (95% CI 0.04 to 0.07). This association did not vary significantly by sex, with 0.05 (0.03 to 0.07) for women and 0.06 (0.04 to 0.09) for men. The association was stronger among those with asthma (0.12; 0.06 to 0.18) compared with those without asthma (0.05; 0.03 to 0.06) (p=0.011). The association of change in respiratory burden score with change in VGDF exposure gave a beta-coefficient of 0.15 (0.05 to 0.19). This association was somewhat greater for men versus women, with coefficients of 0.18 (0.12 to 0.24) and 0.13 (0.07 to 0.19), respectively (p=0.064). The estimate was similar among subjects with asthma (0.18; -0.02 to 0.38) and those without asthma (0.15; 0.11 to 0.19). CONCLUSIONS: Increased BMI and exposure to VGDF were associated with increased respiratory burden scores. The change due to increased BMI was not affected by sex, but subjects with asthma had a significantly larger change than those without. Increased frequency of VGDF exposure was associated with increased respiratory burden score but without statistically significant differences with respect to sex or asthma status. [Description provided by NIOSH]
• Subjects:
  Air Pollutants, Occupational Asthma Asthma, Occupational Body Weight Dust Lung Occupational Exposure Occupational Health Respiratory System Respiratory Tract Diseases Safety Solvents

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• Keywords:
  Exposure assessment; Asthma; Obesity; Body weight; Gases; Vapors; Dusts; Fumes; Occupational exposure; Lung function; Respiratory system disorders; Population based studies
• ISSN:
  2052-4439
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  RHD - Respiratory Health Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  9
• Issue:
  1
• NIOSHTIC Number:
  nn:20064999
• Citation:
  BMJ Open Respir Res 2022 Mar; 9(1):e001186
• Contact Point Address:
  Dr Geir Klepaker, Department of Occupational and Environmental Medicine, Telemark Hospital, Skien, Norway
• Email:
  geir.klepaker@sthf.no
• Federal Fiscal Year:
  2022
• Peer Reviewed:
  True
• Source Full Name:
  BMJ Open Respiratory Research
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:114a07fd7b027dfe9d8db96877ea7b12a52845655b73beb4c909b24ab4e02ecc832ccc8f2a875830ee4b1906111ed0acc823f1ea1d14861e2eccfc9dabe411fc
• Download URL:
  https://stacks.cdc.gov/view/cdc/248623/cdc_248623_DS1.pdf
• File Type:
  [PDF - 539.84 KB ]