Temporary threshold shift in ABRs and DPOAEs following noise exposure in Long-Evans rats.

Details

• Personal Author:
  Murphy, William J. ; van Campen LE
• Description:
  In conjunction with a study of reactive oxygen species induced damage in Long-Evans rats [van Campen et al., ARO abstracts (2001)], the progressions of temporary shifts in auditory brainstem response thresholds and distortion product otoacoustic emission input/output functions were analyzed. Thirty-five rats were exposed to 2 h of 120-dB SPL band-limited noise (7.5-15 kHz). ABR and DPOAE measurements were collected at 1-, 3-, 8-, 72-, and 672-h post-exposure for seven rats per condition. One sham-exposed rat was included in each exposure group. Thresholds for ABR elicited by tone bursts (2, 4, 8, 16, 32 kHz) exhibited the greatest threshold shifts for the 8-, 16- and 32-kHz stimuli. Recovery following noise exposure was greatest for the 72-h group with a lesser recovery for the 672-h group. The DPOAE thresholds (level of the f2 primary stimulus where LDPOAE was 5 dB above the noise floor) exhibited no significant difference for the 72- and 672-h groups. However, the input/output functions for the 72 group exhibited more DPOAE energy than the 672-h group. [Description provided by NIOSH]
• Subjects:
  Age Factors Aging Hearing Hearing Loss Noise Occupational Health Race Factors Safety Sense Organs Sex Characteristics Surveys And Questionnaires

  More +
• Keywords:
  Hearing-level; Hearing-loss; Hearing-acuity; Health-surveys; Age-factors; Age-groups; Information-retrieval-systems; Physical-examination; Racial-factors; Sex-factors; Audiological-testing; Audiometry
• ISSN:
  0001-4966
• Document Type:
  Text
• Genre:
  Abstract or Summary
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DART - Division of Applied Research and Technology
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  109
• Issue:
  5
• NIOSHTIC Number:
  nn:20045248
• Citation:
  J Acoust Soc Am 2001 May; 109(5):2373
• Contact Point Address:
  William J. Murphy, NIOSH, Hearing Loss Prevention Sect., 4676 Columbia Pkwy., Cincinnati, OH 45226-1998
• Federal Fiscal Year:
  2001
• Peer Reviewed:
  False
• Source Full Name:
  Journal of the Acoustical Society of America
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/248262/cdc_248262_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]