Toxicology of 1-->3-beta-glucans: glucans as a marker for fungal exposure.

Details

• Personal Author:
  Castranova, Vincent ; Young S-H
• Description:
  The investigation of indoor air quality has shown that microbial contamination is often a problem in buildings. Recent evidence indicates that fungi are often a part of the picture. A component of the fungal cell wall, 1-->3-ß-glucans not only affect human health, they are a marker for the existence of fungi in environmental samples. Toxicology of 1-->3-ß-Glucans covers the basic chemistry and immunobiology of these substances. The authors begin by introducing current methods for detecting 1-->3-ß-glucans in environmental samples and reviewing risk evaluation in the environment. They go on to discuss numerous topics including likely occupational and environmental exposure, studies suggesting a strong link between environmental glucan concentrations and pulmonary inflammation, and signal transduction pathways and specific receptors. No other book currently available brings together the expertise of leading international researchers to provide a straightforward monograph on the toxicology of 1-->3-ß-glucans. It pulls together current knowledge of these compounds, their effects, measurement, monitoring, and risk assessment. [Description provided by NIOSH]
• Subjects:
  Air Pollution, Indoor Biomarkers Environmental Health Environmental Monitoring Fungi Microbiology Occupational Health Risk Assessment Safety
• Keywords:
  Indoor-air-pollution; Indoor-environmental-quality; Biomarkers; Microorganisms; Microbial-test-systems; Fungal-diseases; Fungal-infections; Fungi; Analytical-processes; Risk-analysis; Exposure-assessment
• ISBN:
  9780415700375
• Publisher:
  CRC Press
• Document Type:
  Text
• Genre:
  Book
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-217
• NIOSHTIC Number:
  nn:20040893
• Citation:
  Young S-H, Castranova V, eds. Boca Raton, FL: CRC Press, 2005 Mar; :1-217
• Editor(s):
  Young S-H; Castranova V
• Federal Fiscal Year:
  2005
• Peer Reviewed:
  False
• Source Full Name:
  Toxicology of 1-->3-beta-glucans: glucans as a marker for fungal exposure
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/248178/cdc_248178_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]