Toxic models of certain disorders of the nervous system - a teaching monograph.

Details

• Personal Author:
  Schaumburg HH
• Description:
  Morphological models of human nervous system disease, developed through animal research, are described. Nervous system conditions are classified according to putative site of attack (neuron cell body, Schwann cell myelin, central peripheral distal axon, predominantly central axon, and proximal axon), and the associated human diseases are listed. Symptoms and chemical causes of neuronopathy, toxic myelinopathy, predominantly central axonopathy, and proximal axonopathy are reviewed. Central peripheral distal axonopathy, the most common peripheral nervous system reaction to exogenous toxins, is discussed and two animal model studies of this condition and human and animal correlations are considered. Industrial, environmental, and pharmaceutical agents associated with toxic axonopathies also are listed. [Description provided by NIOSH]
• Subjects:
  Hazardous Substances Laboratories Nervous System Nervous System Diseases Occupational Health Pathology Safety
• Keywords:
  NIOSH-Publication; Nervous-system-disorders; Laboratory-animals; Toxic-substances; Humans; Clinical-studies; Physiological-systems; Pathology; Neurotoxicity; Peripheral-nervous-system; Neurotoxic-effects
• ISSN:
  0161-813X
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  New York ; Ohio ; OSHA Region 2 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  209-220
• Volume:
  1
• Issue:
  1
• NIOSHTIC Number:
  nn:00091741
• Citation:
  Neurotoxicology 1979 Jan; 1(1):209-220
• Contact Point Address:
  Pathology Albert Einstein Coll of Med 1300 Morris Park Avenue Bronx, N Y 10461
• Federal Fiscal Year:
  1979
• NORA Priority Area:
  Neurotoxic Disorders ; Neurotoxic Effects
• Performing Organization:
  Yeshiva University, New York, New York
• Peer Reviewed:
  True
• Start Date:
  19751101
• Source Full Name:
  Neurotoxicology
• End Date:
  19850331
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/247468/cdc_247468_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]