Prevention of occupational skin diseases from exposure to chromic acid and chromates: use of ascorbic acid.

Details

• Personal Author:
  Samitz MH
• Description:
  A review of preventive measures for the control of the irritant and sensitizing action caused by chromates reveals that ascorbic acid is effective in preventing and treating a variety of such adverse reactions. A 10 percent ascorbic-acid (50817) solution shortens the time required for the healing of skin ulcers produced by potassium- chromate (7789006) in guinea-pigs, while the impregnation of ascorbic-acid into the filters of respirators enhances protection against inhalation of chromic-acid (7738945) mist. A preventive regimen with 10 percent aqueous ascorbic-acid proved effective in the printing industry and in the lithographing industry. [Description provided by NIOSH]
• Subjects:
  Chromium Hypersensitivity Metals Metals, Heavy Occupational Health Personal Protective Equipment Poisoning Preventive Medicine Respiratory Protective Devices Safety Skin Skin Diseases

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• Keywords:
  NIOSH-Publication; NIOSH-Grant; Skin-disorders; Preventive-medicine; Metal-poisoning; Chromium-poisoning; Hypersensitivity; Skin-irritation; Heavy-metals; Vitamins; Skin-protection; Personal-protective-equipment; Respiratory-protection
• ISSN:
  0011-4162
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; Pennsylvania
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• NIOSHTIC Number:
  nn:00036328
• Citation:
  Cutis 1974 Apr; 13:569-574
• Contact Point Address:
  Medicine, Dermatology Univ of Pennsylvania Hospital Duhring Laboratory Building Philadelphia, PA 19104
• CAS Registry Number:
  Chromic acid (H2CrO4) (CAS RN 7738-94-5) ; Dipotassium chromate (K2CrO4) (CAS RN 7789-00-6) ; L-Ascorbic acid (CAS RN 50-81-7)
• Federal Fiscal Year:
  1974
• Performing Organization:
  University of Pennsylvania, Philadelphia, Pennsylvania
• Peer Reviewed:
  True
• Start Date:
  19701201
• Source Full Name:
  Cutis
• End Date:
  19751130
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/247393/cdc_247393_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]