Silicosis and pulmonary cancer.

Details

• Personal Author:
  Beaumont, James J. ; Goldsmith DF ; Schenker M
• Description:
  This report summarized the findings of a research project. In the determination of whether silicotics in California had excess mortality from pulmonary cancer for the period 1950 through 1984, the patients were found to have double the expected rate of mortality from lung cancer. Adjusting for partial smoking information, it was demonstrated that there was a residual risk directly related to silicosis. When examined by industry lung cancer risk indicated that construction had a standardized mortality ratio of 4.04, which could be confounded by asbestos (1332214) exposure. The risk of lung cancer was elevated for mining and metallurgy, but not for other industry groups. For the assessment of whether silicotics had increased mortality from gastric and hematopoietic malignancies, a follow up of the study could not confirm elevated mortality risks for either of those cancers. Lack of funding did not allow for the completion of the last three research aims, which involved the completion of the Registry of silicotics by the inclusion of claims from Southern California and from Federal Sources, validation of silicosis claims via a blind review of chest roentgenograms by two certified readers, and a comparison of smoking habits and work histories of lung cancer cases and matched controls. [Description provided by NIOSH]
• Subjects:
  Asbestos Construction Industry Inorganic Chemicals Lung Lung Diseases Neoplasms Occupational Health Respiratory System Respiratory Tract Diseases Risk Assessment Risk Factors Safety

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• Keywords:
  NIOSH-Grant; Pulmonary-system-disorders; Risk-factors; Risk-analysis; Cancer-rates; Lung-cancer; Respiratory-system-disorders; Asbestos-fibers; Construction-industry; Silicosis
• Series:
  Grant Final Reports
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Final Grant Report
• Place as Subject:
  California ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  OEP - Office of Extramural Programs
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-5
• NIOSHTIC Number:
  nn:00227286
• Citation:
  Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, R01-OH-002726, 1994 Apr; :1-5
• Contact Point Address:
  Internal Medicine University of California Internal Medicine Davis, CA 95616
• CAS Registry Number:
  Asbestos (CAS RN 1332-21-4)
• Federal Fiscal Year:
  1994
• NORA Priority Area:
  Pulmonary System Disorders
• Performing Organization:
  University of California Davis
• Peer Reviewed:
  False
• Start Date:
  19890601
• Source Full Name:
  National Institute for Occupational Safety and Health
• End Date:
  19931130
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/246292/cdc_246292_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]