Interactions of the AH receptor and oxidative signaling.

Details

• Personal Author:
  Baldwin KT ; Burdette HE ; De Fede K ; Ma Q
• Description:
  2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, dioxin) represents the prototype for a class of structurally related halogenated aromatic hydrocarbons (HAHs)1-3. These man-made compounds are mostly by-products of industrial processes involving chlorine chemistry and combustion of fuels. Many such chemicals are widespread and persistent environmental contaminants. TCDD is the most potent among the chemicals; animals exposed to TCDD exhibit a wide range of toxic and adaptive responses. Humans exposed to TCDD exhibit certain skin lesions such as chloracne; the possibility that TCDD exposure causes certain neuro- and psycho-pathological alterations, some forms of cancers and diabetic conditions, and reproductive lesions is a particular concern of public health. [Description provided by NIOSH]
• Subjects:
  Environmental Exposure Environmental Pollution Fuel Oils Hydrocarbons Occupational Health Safety
• Keywords:
  Hydrocarbons; Fuels; Combustion gases; Environmental contamination; Exposure levels
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  336-339
• Volume:
  53
• NIOSHTIC Number:
  nn:20021371
• Citation:
  Dioxin 2001 Sep; 53:336-339
• Federal Fiscal Year:
  2001
• Peer Reviewed:
  False
• Source Full Name:
  Dioxin
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/245802/cdc_245802_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]