In vitro tests for workplace cocarcinogens.

Details

• Corporate Authors:
  National Institute for Occupational Safety and Health
• Description:
  Twenty-five coded test articles were evaluated in the Chinese hamster V79 inhibition of metabolic cooperation assay. By the criteria established in this report, 11 of the test chemicals produced positive responses, four test chemicals produced weak positive responses, 1 chemical enhanced metabolic cooperation, 1 chemical weakly enhanced metabolic cooperation, and 7 produced negative responses. Of the 12 test chemicals previously evaluated in this assay, 10 produced responses in agreement with the previously reported responses. Only two of the test chemicals, benzoyl peroxide and 2,4-dinitrofluorobenzene, produced responses that differed from those previously reported. [Description provided by NIOSH]
• Content Notes:
  in NTRL, no PDF
• Subjects:
  Carcinogens Laboratories Occupational Health Safety Toxicology
• Keywords:
  Toxicology; Hamsters; Laboratory-animals; Carcinogens; In-vitro-analysis
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Funding:
  Contract
• Genre:
  Final Contract Report
• Place as Subject:
  North Carolina ; Ohio ; OSHA Region 4 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DBBS - Division of Biomedical and Behavioral Sciences
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-209
• NIOSHTIC Number:
  nn:20000735
• NTIS Accession Number:
  PB84241066
• Citation:
  Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, Contract 200-82-2520, 1984 May; :1-209
• CAS Registry Number:
  2,4,6,8-Tetradecatetraenoic acid, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9-yl ester (CAS RN 64604-09-7) ; 2-Propynoic acid, 3-phenyl-, ethyl ester (CAS RN 2216-94-6) ; Benzoyl peroxide (CAS RN 94-36-0) ; Catechol (CAS RN 120-80-9) ; Dinitrofluorobenzene (CAS RN 70-34-8) ; Dodecane (CAS RN 112-40-3) ; Hydrogen peroxide (CAS RN 7722-84-1) ; Mezerein (CAS RN 34807-41-5) ; Sodium cyclamate (CAS RN 139-05-9)
• Federal Fiscal Year:
  1984
• Performing Organization:
  Northrop Services, Inc., Research Triangle Park, NC
• Peer Reviewed:
  False
• Source Full Name:
  National Institute for Occupational Safety and Health
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/245750/cdc_245750_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]