Chronic inhalation toxicology study in monkeys and rats exposed to fibrous glass, volume 2, appendices.

Details

• Personal Author:
  Connell MM ; Mitchell RI ; Mosberg AT ; Reif RB ; Thake DC
• Description:
  Data accompanying a chronic toxicity study of fiber glass in monkeys and rats is presented. The protocol and standard operating procedures of the project are given. The methodology for determining clinical chemistry and hematology parameters was presented. Daily concentrations of fiber glass concentrations in the exposure chamber are tabulated. Data used in determining the precision of light, medium, and heavy filter weights is noted. Inertial characteristics of fibers are discussed. Mean weekly body weights of the experimental animals are tabulated. Data analyses of the survival of the experimental animals are given. Coded and tabulated pathology reports for each experimental animal are presented. Particle size distribution data of glass fibers determined from filter samples in the exposure chambers are provided. Procedures for determining the size characteristics of glass fibers deposited in monkey and rat lungs are noted. Three dimensional plots of glass fiber particle size distributions in monkey and rat lungs are presented. Calculated values of the lung burden of glass fibers in rats and monkeys are listed. [Description provided by NIOSH]
• Content Notes:
  in NTRL, no PDF
• Subjects:
  Dermatitis Glass Occupational Health Particulate Matter Respiratory Tract Diseases Safety Toxicology
• Keywords:
  Fibrous-glass; Respiratory-system-disorders; Toxicology; Fiber-deposition; Dermatitis
• Document Type:
  Text
• Funding:
  Contract
• Genre:
  Final Contract Report
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DBBS - Division of Biomedical and Behavioral Sciences
• Topic:
  Workplace Safety & Health
• Location:
  North America
• NIOSHTIC Number:
  nn:20000713
• NTIS Accession Number:
  PB85222214
• Citation:
  NIOSH 1982 Oct; :1-542
• Federal Fiscal Year:
  1983
• NORA Priority Area:
  Pulmonary System Disorders
• Performing Organization:
  Battelle Columbus Labs., Columbus, OH
• Peer Reviewed:
  False
• Source Full Name:
  National Institute for Occupational Safety and Health
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/245736/cdc_245736_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]