Cytogenetic study of workers exposed to ethylene dibromide.

Details

• Personal Author:
  Steenland, Kyle
• Description:
  A cytogenetic study of papaya packing facility workers in Hawaii was conducted to investigate the health effects of exposure to the fumigant ethylene-dibromide (106934) (EDB), particularly regarding cancer. This study was described as part of a text book and took the reader through the same steps that the investigator took when conducting the actual study to allow the student to solve the same problems that the investigator solved in the course of the study. The first step was to conduct an industrial hygiene survey characterizing exposure at six papaya packing facilities. A total of 60 workers from the papaya facility and 40 nonexposed workers from a nearby sugar facility participated. The industrial hygiene survey confirmed that the papaya facility workers were exposed to levels of EDB averaging about 100 parts per million (ppm). Exposure levels differed for three principal job categories, sorter/packer, forklift operator, and fumigator. Further analysis compared length of exposure, and whether or not the workers had skin contact or smelled the chemical. The results indicated that at these relatively low levels of exposure, there was no association with sister chromatid exchange frequencies, indicating there was no cytogenetic effect for these workers. [Description provided by NIOSH]
• Subjects:
  Chromosomes Epidemiology Food-Processing Industry Occupational Exposure Occupational Health Risk Assessment Risk Factors Safety
• Keywords:
  Genotoxic-effects; Chromosome-disorders; Chromosome-damage; Risk-factors; Epidemiology; Occupational-exposure; Food-processing-industry
• ISBN:
  9780195068313
• Publisher:
  Oxford University Press
• Document Type:
  Text
• Genre:
  Book
• Place as Subject:
  Hawaii ; New York ; Ohio ; OSHA Region 2 ; OSHA Region 5 ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  142-156
• NIOSHTIC Number:
  nn:00238247
• Citation:
  Case studies in occupational epidemiology. Steenland K, ed. New York: Oxford University Press, 1993 Jan; :142-156
• CAS Registry Number:
  1,2-Dibromoethane (CAS RN 106-93-4)
• Editor(s):
  Steenland K
• Federal Fiscal Year:
  1993
• Peer Reviewed:
  False
• Source Full Name:
  Case studies in occupational epidemiology
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/243601/cdc_243601_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]