The genetics of noise-induced hearing loss.

Details

• Personal Author:
  Cortopassi G ; Davis, Rickie R. ; Erway LC
• Description:
  The differences in susceptibility to noise induced hearing loss (NIHL) which may be attributed to genetic factors were discussed. The use of genetic, inbred strains of mice as models for hearing studies was explained; the advantages of using a murine model included small size, easy breeding, short time between generations, production of identical offspring, and the fact that much of their genome has been mapped for homologies with the human genome. The use of various strains in studies of genes and age related or noise related hearing loss was described. Studies were underway to characterize the effect of noise on the ahl-1 genotypes. Human implications associated with these studies were discussed. The authors conclude that by identifying human genes responsible for noise sensitivity, it may be possible to warn workers prior to noise exposure and to prevent NIHL. Workers who may have particular sensitivity to NIHL would be provided with higher levels of hearing protection or by working shorter amounts of time in noisy situations. [Description provided by NIOSH]
• Subjects:
  Age Factors Genetics Hearing Loss Hearing Loss, Noise-Induced Laboratories Noise Occupational Health Risk Assessment Risk Factors Safety
• Keywords:
  Genetic-factors; Noise-exposure; Risk-factors; Laboratory-animals; Noise-induced-hearing-loss; Age-factors; Hearing-loss; Genetics
• ISBN:
  9789518021028
• ISSN:
  1237-6183
• Publisher:
  Finnish Institute of Occupational Health
• Document Type:
  Text
• Genre:
  Proceedings
• Place as Subject:
  California ; Ohio ; OSHA Region 5 ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DBBS - Division of Biomedical and Behavioral Sciences
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  31-34
• NIOSHTIC Number:
  nn:00229718
• Citation:
  Sixth US-Finnish Joint Symposium on Occupational Health and Safety, People and Work, Proceedings of the Sixth FIOH-NIOSH Joint Symposium on Occupational Health and Safety, 8-10 August 1995, Espoo, Finland. People and Work - Research Reports 3. H. Nordman, J. Starck, A. Tossavainen, E. Viikari-Juntura, eds. Helsinki, Finland: Finnish Institute of Occupational Health; 1995 Aug; :31-34
• Editor(s):
  Nordman H; Starck J; Tossavainen A; Viikari-Juntura E
• Federal Fiscal Year:
  1995
• NORA Priority Area:
  Disease and Injury: Hearing Loss
• Peer Reviewed:
  False
• Source Full Name:
  Sixth US-Finnish Joint Symposium on Occupational Health and Safety, People and Work, Proceedings of the Sixth FIOH-NIOSH Joint Symposium on Occupational Health and Safety, 8-10 August 1995, Espoo, Finland. People and Work - Research Reports 3
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/243434/cdc_243434_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]