Details:

Alternative Title:
Emerg Infect Dis
Publisher's site:
http://dx.doi.org/10.3201/eid1704.101562
Personal Author:
Roest, Hendrik I.J. ; Ruuls, Robin C. ; Tilburg, Jeroen J.H.C. ; Nabuurs-Franssen, Marrigje H. ; Klaassen, Corné H.W. ; ... More +
Roest, Hendrik I.J. ; Ruuls, Robin C. ; Tilburg, Jeroen J.H.C. ; Nabuurs-Franssen, Marrigje H. ; Klaassen, Corné H.W. ; Vellema, Piet ; van den Brom, René ; Dercksen, Daan ; Wouda, Willem ; Spierenburg, Marcel A.H. ; van der Spek, Arco N. ; Buijs, Rob ; de Boer, Albert G. ; Willemsen, Peter Th.J. ; van Zijderveld, Fred G. Less -
Description:
Q fever is a zoonosis caused by the bacterium Coxiella burnetii. One of the largest reported outbreaks of Q fever in humans occurred in the Netherlands starting in 2007; epidemiologic investigations identified small ruminants as the source. To determine the genetic background of C. burnetii in domestic ruminants responsible for the human Q fever outbreak, we genotyped 126 C. burnetii-positive samples from ruminants by using a 10-loci multilocus variable-number tandem-repeat analyses panel and compared them with internationally known genotypes. One unique genotype predominated in dairy goat herds and 1 sheep herd in the human Q fever outbreak area in the south of the Netherlands. On the basis of 4 loci, this genotype is similar to a human genotype from the Netherlands. This finding strengthens the probability that this genotype of C. burnetii is responsible for the human Q fever epidemic in the Netherlands.
Subject:
[+]
Animals
Bacteria
Bacterial Typing Techniques
Cattle
Coxiella Burnetii
Disease Outbreaks
Genotype
Goat
Goat Diseases
Goats
Humans
Molecular Epidemiology
Multilocus Sequence Typing
Netherlands
Phylogeny
Q Fever
Research
Ruminants
Sheep
Sheep Diseases
The Netherlands
Zoonoses
Sheep

Source:
Emerg Infect Dis. 17(4):668-675.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:c08a63cf2290bae6e1ab20dd9d6a9837c72e39e2302ea2f9d985addecad4edfd
File Type:

Supporting Files

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