Effects of neurotoxic agents on behavior.

Details

• Personal Author:
  Johnson BL
• Description:
  The effects of neurotoxins on human behavior are reviewed. Three ways in which behavioral effects of chemicals are measured are self reporting, observation by trained observers, and performance of structured tasks. Acute intoxication involves dizziness, confusion, lethargy, and motor incoordination. Subacute and chronic exposure affects memory and problem solving. Very few neurotoxins have known effects based on epidemiological studies. Some chemicals that have been studied include carbon-disulfide (75150), carbon-monoxide (630080), formaldehyde (50000), lead (7439921), mercury (7439976), and trichloroethylene (79016). Most epidemiological studies employ a battery of psychophysiological tests, which test intelligence, memory, coordination, reaction time, visual function, and alertness. Human laboratory investigations address behavioral effects of neurotoxins measured under acute, low concentration exposure conditions, simulating a work day. The author concludes that there is a need for research to study interactions among neurotoxins. [Description provided by NIOSH]
• Subjects:
  Behavior Mental Disorders Mental Health Nervous System Occupational Health Safety Toxicology
• Keywords:
  Medical-research; Neurotoxic-effects; Toxicology; Qualitative-analysis; Behavioral-disorders; Analytical-methods; Industrial-chemicals; Psychological-testing; Drug-interaction; Biological-effects
• ISSN:
  0165-2214
• Document Type:
  Text
• Genre:
  Journal Article
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DBBS - Division of Biomedical and Behavioral Sciences
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  105-112
• Volume:
  11
• NIOSHTIC Number:
  nn:00129235
• Citation:
  Dev Toxicol Environ Sci 1983 Jan; 11:105-112
• CAS Registry Number:
  Carbon disulfide (CAS RN 75-15-0) ; Carbon monoxide (CAS RN 630-08-0) ; Formaldehyde (CAS RN 50-00-0) ; Lead (CAS RN 7439-92-1) ; Mercury (CAS RN 7439-97-6) ; Trichloroethylene (CAS RN 79-01-6)
• Federal Fiscal Year:
  1983
• NORA Priority Area:
  Neurotoxic Disorders ; Neurotoxic Effects
• Peer Reviewed:
  True
• Source Full Name:
  Developments in Toxicology and Environmental Science
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/241579/cdc_241579_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]