Interactions of mercury, cadmium, selenium, tellurium, arsenic and beryllium.

Details

• Personal Author:
  Groth DH ; Mackay G ; Stettler L
• Description:
  The interactions of mercury (7439976), cadmium (7440439), selenium (7782492), tellurium (13494809), arsenic (7440382), and beryllium (7440417) in elemental carcinogenesis are examined. A hypothesis relating ionization potentials to covalent bond stabilities and to organic/inorganic complexes to explain elemental carcinogenesis at a molecular level is presented. Results are discussed from a variety of carcinogenicity studies with beryllium alone, interactions with mercury and selenium, and interactions with arsenic and tellurium. The authors suggest that these metals are carcinogens by virtue of hypothetical ability to form exceptionally stable, four membered, covalent, coordination complexes with nucleic acids and other organic compounds. [Description provided by NIOSH]
• Subjects:
  Carcinogens Chemistry Metals Occupational Health Safety
• Keywords:
  Carcinogenesis; Carcinogens; Organo-metallic-compounds; Physical-properties; Chemical-properties; Metallic-poisons;
• Document Type:
  Text
• Genre:
  Guidance
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• NIOSHTIC Number:
  nn:00126315
• Citation:
  Effects and dose-response relationships of toxic metals 1976 Jan; :528-543
• CAS Registry Number:
  Arsenic (CAS RN 7440-38-2) ; Beryllium (CAS RN 7440-41-7) ; Cadmium (CAS RN 7440-43-9) ; Mercury (CAS RN 7439-97-6) ; Selenium (CAS RN 7782-49-2) ; Tellurium (CAS RN 13494-80-9)
• Federal Fiscal Year:
  1976
• Peer Reviewed:
  False
• Source Full Name:
  Effects and dose-response relationships of toxic metals
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/241565/cdc_241565_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]