Transmission of Guanarito and Pirital Viruses among Wild Rodents, Venezuela
Published Date:Dec 2011
Source:Emerg Infect Dis. 17(12):2209-2215.
Communicable Diseases, Emerging
Pirital Virus Arenaviridae
Venezuelan Hemorrhagic Fever
Funding:AI-39800/AI/NIAID NIH HHS/United States
AI-67947/AI/NIAID NIH HHS/United States
Description:Samples from rodents captured on a farm in Venezuela in February 1997 were tested for arenavirus, antibody against Guanarito virus (GTOV), and antibody against Pirital virus (PIRV). Thirty-one (48.4%) of 64 short-tailed cane mice (Zygodontomys brevicauda) were infected with GTOV, 1 Alston's cotton rat (Sigmodon alstoni) was infected with GTOV, and 36 (64.3%) of 56 other Alston's cotton rats were infected with PIRV. The results of analyses of field and laboratory data suggested that horizontal transmission is the dominant mode of GTOV transmission in Z. brevicauda mice and that vertical transmission is an important mode of PIRV transmission in S. alstoni rats. The results also suggested that bodily secretions and excretions from most GTOV-infected short-tailed cane mice and most PIRV-infected Alston's cotton rats may transmit the viruses to humans.
image/gif image/jpeg text/plain text/plain
You May Also Like: