Serious Invasive Saffold Virus Infections in Children, 2009

Nielsen, Alex Christian Yde; Böttiger, Blenda; Banner, Jytte; Hoffmann, Thomas; Nielsen, Lars Peter

doi:10.3201/eid1801.110725

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Serious Invasive Saffold Virus Infections in Children, 2009

Published Date:

Jan 2012

Publisher's site:

http://dx.doi.org/10.3201/eid1801.110725 New Site Icon

Source:

Emerg Infect Dis. 18(1):7-12.

[PDF-245.32 KB]

Details:

Personal Authors:

Nielsen, Alex Christian Yde ; Böttiger, Blenda ; Banner, Jytte ; Hoffmann, Thomas ; Nielsen, Lars Peter ;

Keywords:

[+]

Description:

The first human virus in the genus Cardiovirus was described in 2007 and named Saffold virus (SAFV). Cardioviruses can cause severe infections of the myocardium and central nervous system in animals, but SAFV has not yet been convincingly associated with disease in humans. To study a possible association between SAFV and infections in the human central nervous system, we designed a real-time PCR for SAFV and tested cerebrospinal fluid (CSF) samples from children <4 years of age. SAFV was detected in 2 children: in the CSF and a fecal sample from 1 child with monosymptomatic ataxia caused by cerebellitis; and in the CSF, blood, and myocardium of another child who died suddenly with no history of illness. Virus from each child was sequenced and shown to be SAFV type 2. These findings demonstrate that SAFV can cause serious invasive infection in children.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Supporting Files:

	11-0725-F1.gif	image/gif
	11-0725-F1.jpg	image/jpeg
	11-0725-F2.gif	image/gif
	11-0725-F2.jpg	image/jpeg
	11-0725_finalR.nxml	text/plain
	license.txt	text/plain

No Related Documents.

You May Also Like:

Co-Circulation and Persistence of Genetically Distinct Saffold Viruses, Denmark

Personal Author:

Nielsen, Alex Christian Yde; Gyhrs, Mette Louise; Holmes, Edward C.; Cui, Jie;

Published:

Oct 2012

Source:

Emerg Infect Dis. 18(10):1694-1696.

File Type:

[PDF - 183.39 KB]
New Saffold Cardiovirus in Children, China

Personal Author:

Xu, Zi-Qian; Cheng, Wei-Xia; Qi, Hong-Mei; Cui, Shu-Xian; Jin, Yu; Duan, Zhao-Jun;

Published:

Jun 2009

Source:

Emerg Infect Dis. 15(6):993-994.

File Type:

[PDF - 387.38 KB]
Pathogenic Leptospira spp. in Bats, Madagascar and Union of the Comoros

Personal Author:

Lagadec, Erwan; Gomard, Yann; Guernier, Vanina; Dietrich, Muriel; Pascalis, Hervé; Temmam, Sarah; Ramasindrazana, Beza; Goodman, Steven M.; Tortosa, Pablo; Dellagi, Koussay;

Published:

Oct 2012

Source:

Emerg Infect Dis. 18(10):1696-1698.

File Type:

[PDF - 204.19 KB]
Diversity of picornaviruses in rural Bolivia

Personal Author:

Nix, W. Allan; Khetsuriani, Nino; Peñaranda, Silvia; Maher, Kaija; Venczel, Linda; Cselkó, Zsuzsa; Freire, Maria Cecelia; Cisterna, Daniel; Lema, Cristina L.; Rosales, Patricia; Rodriguez, Jacqueline R.; Rodriguez, Wilma; Halkyer, Percy; Ronveaux, Olivier; Pallansch, Mark A.; Oberste, M. Steven;

Published:

Jun 26 2013

Source:

J Gen Virol. 94(0 9):2017-2028.

Description:

The family Picornaviridae is a large and diverse group of viruses that infect humans and animals. Picornaviruses are among the most common infections of humans and cause a wide spectrum of acute human disease. This study began as an investigation of ...

File Type:

[PDF - 2.48 MB]
Saffold Cardioviruses in Children with Diarrhea, Thailand

Personal Author:

Khamrin, Pattara; Chaimongkol, Natthawan; Nantachit, Nattika; Okitsu, Shoko; Ushijima, Hiroshi; Maneekarn, Niwat;

Published:

Jun 2011

Source:

Emerg Infect Dis. 17(6):1150-1152.

File Type:

[PDF - 167.76 KB]