Occupational Risk Factors for SARS-CoV-2 Seropositivity in Healthcare Workers: Results of a Longitudinal Cohort

Details

• Personal Author:
  Abad Q-A ; Fazen LE ; Liu J ; Redlich CA ; Santiago R ; Smith RF ; Wisnewski AV
• Description:
  Objective: The aim of the study is to evaluate COVID-19 risk factors among healthcare workers (HCWs) before vaccine-induced immunity. Methods: We conducted a longitudinal cohort study of HCWs (N = 1233) with SARS-CoV-2 immunoglobulin G quantification by ELISA and repeated surveys over 9 months. Risk factors were assessed by multivariable-adjusted logistic regression and Cox proportional hazards models. Results: SARS-CoV-2 immunoglobulin G was associated with work in internal medicine (odds ratio [OR], 2.77; 95% confidence interval [CI], 1.05-8.26) and role of physician-in-training (OR, 2.55; 95% CI, 1.08-6.43), including interns (OR, 4.22; 95% CI, 1.20-14.00) and resident physicians (OR, 3.14; 95% CI, 1.24-8.33). Odds were lower among staff confident in N95 use (OR, 0.55; 95% CI, 0.31-0.96) and decreased over the follow-up. Conclusions: Excess COVID-19 risk observed among physicians-in-training early in the COVID-19 pandemic was reduced with improved occupational health interventions before vaccinations. [Description provided by NIOSH]
• Subjects:
  Cohort Studies Communicable Diseases Health Personnel Occupational Health Risk Assessment Safety
• Keywords:
  Author Keywords: COVID-19 Cohort Studies COVID-19 Health Care Personnel Health Care Worker Health Care Workers Infection Prevention Infectious Diseases Longitudinal Study Occupational Risk Factors Physicians Prospective Cohort Risk Analysis SARS-CoV-2

  More +
• ISSN:
  1076-2752
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Connecticut ; Maryland ; OSHA Region 1 ; OSHA Region 3 ; OSHA Region 6 ; Texas
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  65
• Issue:
  6
• NIOSHTIC Number:
  nn:20067616
• Citation:
  J Occup Environ Med 2023 Jun; 65(6):521-528
• Contact Point Address:
  Louis Fazen, MD, PhD, 615 N. Wolfe Street, Baltimore, MD 21205
• Email:
  louis.fazen@jhmi.edu
• Federal Fiscal Year:
  2023
• Performing Organization:
  Yale University School of Medicine
• Peer Reviewed:
  True
• Start Date:
  20010701
• Source Full Name:
  Journal of Occupational and Environmental Medicine
• End Date:
  20260630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:3ccfde9170940a5e9e47ba99ab4e9054c9a8e27197ee85dc08ddec6f8cd79261e17c253c5a9191e0b62cc08ce83720350444803c935d883832d317efefbc2aee
• Download URL:
  https://stacks.cdc.gov/view/cdc/231509/cdc_231509_DS1.pdf
• File Type:
  [PDF - 411.39 KB ]