Controlled Surface Radical Graft Polymerization of N-Halamine Monomers on Polyester Fabrics and Potential Application in Bioprotective Medical Scrubs

Details

• Personal Author:
  Dong Q ; Huang C ; Ma Y ; Sun G ; Xiao L ; Zhang Z
• Description:
  Embedding medical scrubs with robust biocidal functions could potentially reduce pathogen cross-contamination and healthcare-associated infections. Here, a halamine precursor monomer, 1-acryloyl-2,2,5,5-tetramethylimidazolidin-4-one (ACTMIO), was covalently grafted to a poly(ethylene terephthalate) (PET) fabric, which is a common textile material used in medical scrubs, via a controlled free radical graft polymerization reaction using a "pad-dry-cure" finishing process. Based on a computational model and Hansen solubility theory, an ideal free radical reaction system was designed and implemented. The obtained ACTMIO-grafted (H-PET-g-ACTMIO) fabrics exhibited high grafting ratios of the monomers, desired properties of improved hydrophilicity, large active chlorine capacity, promising chlorine rechargeability, and desirable washing durability due to the robust covalent bonds between halamine moieties and PET fabrics. The chlorinated H-PET-g-ACTMIO fabric demonstrated powerful and regenerable biocidal performance against pathogenic bacteria, revealing the great application potential as a bioprotective medical textile. In addition, the successful application of Hansen solubility theory in surface modification of chemically inert polyester fibers provides a good example of controlling free radical polymerization reactions on textile materials. [Description provided by NIOSH]
• Subjects:
  Occupational Health Personal Protective Equipment Polymers Protective Clothing Safety Textile Industry
• Keywords:
  Antibacterial Agents Antimicrobials Author Keywords: Controlled Surface Modification Biocides Bioprotective Medical Scrub Fabrics Halamine Hansen Solubility Parameters Nosocomial Infections Pathogens Polyester Fabric Protective Clothing Textiles

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• ISSN:
  2637-6105
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  California ; Iowa ; OSHA Region 7 ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  4
• Issue:
  9
• NIOSHTIC Number:
  nn:20067837
• Citation:
  ACS Appl Polym Mater 2022 Sep; 4(9):6760-6769
• Contact Point Address:
  Gang Sun, Department of Biological and Agricultural Engineering, University of California, Davis, California 95616, United States
• Email:
  gysun@ucdavis.edu
• Federal Fiscal Year:
  2022
• Performing Organization:
  Iowa State University
• Peer Reviewed:
  True
• Start Date:
  20210930
• Source Full Name:
  ACS Applied Polymer Materials
• End Date:
  20250929
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:be88c119f63505afe00e2bc9089b06448f73eeccb96f857ca62dd01758548afa5f3ca3b0ba2b9619bb7272013d0d9d6b72a9d0c5e13ef765f86b289971f7cc3d
• Download URL:
  https://stacks.cdc.gov/view/cdc/230092/cdc_230092_DS1.pdf
• File Type:
  [PDF - 5.45 MB ]