Post-9/11 Excess Risk of Thyroid Cancer: Surveillance or Exposure?

Details

• Personal Author:
  Cerutti JM ; Genden E ; Rapp J ; Riggins GJ ; Taioli E ; Van Gerwen M
• Description:
  An excess risk of thyroid cancer has been reported in different World Trade Center (WTC)-dust exposed cohorts. Increased surveillance of these cohorts has been suggested as a potential explanation of this reported excess thyroid cancer risk leading to an increased diagnosis of earlier-stage thyroid cancers. However, the uncertainty to what extent surveillance or physician bias may be contributing to the reported incidence of thyroid cancer in WTC-dust exposed populations remains, highlighting the need to investigate a potential causal link between WTC dust exposure and thyroid cancer. Future studies are therefore indicated to investigate potential consequences of WTC dust exposure on the thyroid gland. Studies of the heavily exposed populations offer the possibility to better understand the mechanisms behind the exposure to a variety of environmental contaminants, and may provide useful insights into exposures harmful to the thyroid. These can be used in risk stratification when implementing screening in high-risk populations and may inform shared decision-making regarding the extent of thyroid cancer treatment. [Description provided by NIOSH]
• Subjects:
  Dust Emergency Responders Environmental Exposure Neoplasms Occupational Health Risk Assessment Risk Factors Safety September 11 Terrorist Attacks
• Keywords:
  Author Keywords: World Trade Center Cancer Carcinogens Contaminants Dust Exposure Dusts Emergency Medical Services Workers Emergency Medical Technician Emergency Responders EMS EMT Endocrine Disrupting Chemicals Environmental Exposure Exposure Levels Fire Fighter First Responders Overdiagnosis Risk Factors Surveillance Thyroid Cancers Thyroid Gland Disorders World Trade Center WTC

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• ISSN:
  0271-3586
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Journal Article
• Place as Subject:
  Maryland ; New York ; OSHA Region 2 ; OSHA Region 3
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  64
• Issue:
  10
• NIOSHTIC Number:
  nn:20062945
• Citation:
  Am J Ind Med 2021 Oct; 64(10):881-884
• Contact Point Address:
  Maaike van Gerwen, MD, PhD, Department of Otolaryngology- Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl, Box 1189, New York, NY 10029
• Email:
  Maaike.vangerwen@mountsinai.org
• Federal Fiscal Year:
  2022
• Performing Organization:
  Icahn School of Medicine at Mount Sinai
• Peer Reviewed:
  True
• Start Date:
  20190701
• Source Full Name:
  American Journal of Industrial Medicine
• End Date:
  20210630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:339b8debb7e7505bfd2d9e8dcf9416d33b07a0f1d92ecb5052193dd978329c1f0e3abbbbd29685bfa91bf14f8c82dcc9b94d41f98cf204a1dd60ad48c8fc800d
• Download URL:
  https://stacks.cdc.gov/view/cdc/226105/cdc_226105_DS1.pdf
• File Type:
  [PDF - 263.12 KB ]