Development and Validation of a Diabetes Risk Score Among Two Populations

Details

• Personal Author:
  Cragle D ; Golden A ; Newman, Lee S. ; Schwatka, Natalie V. ; Smith DE ; Tran M
• Description:
  The purpose of this study was to assess the validity of a practical diabetes risk score amongst two heterogenous populations, a working population and a non-working population. Study population 1 (n = 2,089) participated in a large-scale screening program offered to retired workers to discover previously undetected/incipient chronic illness. Study population 2 (n = 3,293) was part of a Colorado worksite wellness program health risk assessment. We assessed the relationship between a continuous diabetes risk score at baseline and development of diabetes in the future using logistic regression. Receiver operating curves and sensitivity/specificity of the models were calculated. Across both study populations, we observed that participants with diabetes at follow-up had higher diabetes risk scores at baseline than participants who did not have diabetes at follow-up. On average, the odds ratio of developing diabetes in the future was 1.38 (95% CI: 1.26-1.50, p < 0.0001) for study population 1 and 1.68 (95% CI: 1.45-1.95, p-value < 0.0001) for study population 2. These findings indicate that the diabetes risk score may be generalizable to diverse individuals, and thus potentially a population level diabetes screening tool. Minimally-invasive diabetes risk scores can aid in the identification of sub-populations of individuals at risk for diabetes. [Description provided by NIOSH]
• Subjects:
  Blood Demography Hematologic Diseases Occupational Health Risk Assessment Risk Factors Safety
• Keywords:
  Blood Sugar Disorders Demographic Characteristics Humans Medical Screening Models Regression Analysis Risk Analysis Risk Assessment Risk Factors Sampling Sampling Methods Sensitivity Testing

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• ISSN:
  1932-6203
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Journal Article
• Place as Subject:
  Colorado ; New York ; OSHA Region 2 ; OSHA Region 4 ; OSHA Region 8 ; Tennessee
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  16
• Issue:
  1
• NIOSHTIC Number:
  nn:20062915
• Citation:
  PLoS One 2021 Jan; 16(1):e0245716
• Contact Point Address:
  Natalie V. Schwatka, Center for Health, Work & Environment, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, Colorado, United States of America
• Email:
  natalie.schwatka@cuanschutz.edu
• Federal Fiscal Year:
  2021
• Performing Organization:
  University of Colorado Denver, Aurora
• Peer Reviewed:
  True
• Start Date:
  20160901
• Source Full Name:
  PLoS One
• End Date:
  20260831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:aa6a61c7a8349f16e7e040e2c84a933db4fcc474a1efd4a0828642bc5f4d440b0a2cb5736b6078581bf14c2115077bc04da3aee733003a411098d8eb41619718
• Download URL:
  https://stacks.cdc.gov/view/cdc/226084/cdc_226084_DS1.pdf
• File Type:
  [PDF - 533.70 KB ]