Traffic-Related Air Pollution Exposure in the First Year of Life and Behavioral Scores at 7 Years of Age

Details

• Journal Article:
  Environmental Health Perspectives
• Personal Author:
  Newman, Nicholas C. ; Ryan, Patrick ; LeMasters, Grace ; Levin, Linda ; Bernstein, David ; Khurana Hershey, Gurjit K. ; Lockey, James E. ; Villareal, Manuel ; Reponen, Tiina ; Grinshpun, Sergey A. ; Sucharew, Heidi ; Dietrich, Kim N.
• Description:
  BACKGROUND: There is increasing concern about the potential effects of traffic-related air pollution (TRAP) on the developing brain. The impact of TRAP exposure on childhood behavior is not fully understood because of limited epidemiologic studies. OBJECTIVE: We explored the association between early-life exposure to TRAP using a surrogate, elemental carbon attributed to traffic (ECAT), and attention deficit/hyperactivity disorder (ADHD) symptoms at 7 years of age. METHODS: From the Cincinnati Childhood Allergy and Air Pollution Study (CCAAPS) birth cohort we collected data on exposure to ECAT during infancy and behavioral scores at 7 years of age. Children enrolled in CCAAPS had at least one atopic parent and a birth residence either < 400 m or > 1,500 m from a major highway. Children were followed from infancy through 7 years of age. ECAT exposure during the first year of life was estimated based on measurements from 27 air sampling sites and land use regression modeling. Parents completed the Behavioral Assessment System for Children, 2nd Edition, when the child was 7 years of age. ADHD-related symptoms were assessed using the Hyperactivity, Attention Problems, Aggression, Conduct Problems, and Atypicality subscales. RESULTS: Exposure to the highest tertile of ECAT during the child's first year of life was significantly associated with Hyperactivity T-scores in the "at risk" range at 7 years of age, after adjustment [adjusted odds ratio (aOR) = 1.7; 95% CI: 1.0, 2.7]. Stratification by maternal education revealed a stronger association in children whose mothers had higher education (aOR = 2.3; 95% CI: 1.3, 4.1). CONCLUSIONS: ECAT exposure during infancy was associated with higher Hyperactivity scores in children; this association was limited to children whose mothers had more than a high school education. [Description provided by NIOSH]
• Subjects:
  Air Pollutants, Occupational Air Pollution Air Pollution, Indoor Attention Deficit Disorder With Hyperactivity Automobiles Child Dust Environmental Exposure Environmental Monitoring Epidemiology Hazardous Substances Infant Linear Models Mental Health Nervous System Occupational Health Particulate Matter Petroleum Risk Assessment Risk Factors Safety

  More +
• Keywords:
  Author Keywords: Attention Deficit/Hyperactivity Disorder; Child Behavior; Epidemiology; Land Use Regression; Traffic-related Air Pollution Pollution; Air-contamination; Air-quality; Airborne-particles; Airborne-dusts; Motor-vehicles; Health-hazards; Humans; Children; Brain-function; Exposure-levels; Risk-factors; Behavior; Epidemiology; Statistical-analysis; Air-sampling; Particulates;
• Source:
  Environ Health Perspect 2013 Jun; 121(6):731-736
• ISSN:
  0091-6765
• Pubmed ID:
  23694812
• Pubmed Central ID:
  PMC3672910
• Document Type:
  Text
• Funding:
  P30-ES006069/ES/NIEHS NIH HHS/United States ; R01 ES019890/ES/NIEHS NIH HHS/United States ; R01-ES019890/ES/NIEHS NIH HHS/United States ; R01-ES11170/ES/NIEHS NIH HHS/United States ; T32-ES10957/ES/NIEHS NIH HHS/United States ; T42-OH008432/OH/NIOSH CDC HHS/United States ; UL1 TR000077/TR/NCATS NIH HHS/United States
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  6 pdf pages
• Volume:
  121
• Issue:
  6
• NIOSHTIC Number:
  nn:20043396
• Contact Point Address:
  Nicholas C. Newman, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave., MLC 7035, Cincinnati, OH 45229
• Email:
  nicholas.newman@cchmc.org
• Federal Fiscal Year:
  2013
• Performing Organization:
  University of Cincinnati
• Peer Reviewed:
  True
• Collection(s):
  National Institute for Occupational Safety and Health CDC Public Access
• Main Document Checksum:
  urn:sha-512:9bdd57bdfe6545a9d53d18a0359e9e366d98e8cabf7f216c38b7d379bc0e6b7455da26014bc6edf6a1b593af7bdc1fc330058080e4680967894b717f1124442b
• Download URL:
  https://stacks.cdc.gov/view/cdc/22601/cdc_22601_DS1.pdf
• File Type:
  [PDF - 188.80 KB ]