Risk of Spina Bifida and Maternal Cigarette, Alcohol, and Coffee Use during the First Month of Pregnancy

Benedum, Corey M.; Yazdy, Mahsa M.; Mitchell, Allen A.; Werler, Martha M.

doi:10.3390/ijerph10083263

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Risk of Spina Bifida and Maternal Cigarette, Alcohol, and Coffee Use during the First Month of Pregnancy

Published Date:

Aug 02 2013

Publisher's site:

http://dx.doi.org/10.3390/ijerph10083263 New Site Icon

Source:

Int J Environ Res Public Health. 2013; 10(8):3263-3281.

[PDF - 707.93 KB]

Details:

Personal Authors:

Benedum, Corey M. ; Yazdy, Mahsa M. ; Mitchell, Allen A. ; Werler, Martha M. ;

Keywords:

[+]

Pubmed ID:

23917813

Pubmed Central ID:

PMC3774437

Description:

This study was conducted to assess the association between the risks of spina bifida (SB) in relation to cigarette, alcohol, and caffeine consumption by women during the first month of pregnancy. Between 1988-2012, this multi-center case-control study interviewed mothers of 776 SB cases and 8,756 controls about pregnancy events and exposures. We evaluated cigarette smoking, frequency of alcohol drinking, and caffeine intake during the first lunar month of pregnancy in relation to SB risk. Logistic regression models were used to calculate adjusted odds ratios and 95% confidence intervals. Levels of cigarette smoking (1-9 and ≥10/day), alcohol intake (average ≥4 drinks/day) and caffeine intake (<1, 1, and ≥2 cups/day) were not likely to be associated with increased risk of SB. Further, results were similar among women who ingested less than the recommended amount of folic acid (400 μg/day).

Document Type:

Journal Article

Collection(s):

CDC Public Access

Funding:

DD000697/DD/NCBDD CDC HHS/United States

Supporting Files:

ijerph-10-03263-g001.gif	image/gif
ijerph-10-03263-g001.jpg	image/jpeg
ijerph-10-03263-i001.jpg	image/jpeg
ijerph-10-03263.nxml	text/plain
license.txt	text/plain

No Related Documents.

You May Also Like:

Maternal Tea Consumption during Early Pregnancy and the Risk of Spina Bifida

Personal Author:

Yazdy, Mahsa M.; Tinker, Sarah C.; Mitchell, Allen A.; Demmer, Laurie A.; Werler, Martha M.;

Published:

May 29 2012

Source:

Birth Defects Res A Clin Mol Teratol. 94(10):756-761.

Description:

Studies have demonstrated that catechin, an antioxidant found in tea, can reduce the bioavailability of folate. Because periconceptional folic acid intake has been demonstrated to reduce the risk of spina bifida, tea consumption may put pregnant wome...

File Type:

[PDF - 335.26 KB]
Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects

Personal Author:

Houk, Vernon N.; Oakley, Godfrey P.; Erickson, J. David; Mulinare, Joseph; James, Levy M.;

Corporate Author:

National Center for Environmental Health (U.S.). Division of Birth Defects and Developmental Disabilities. Birth Defects and Genetic Diseases Branch.

Published:

September 11, 1992

Source:

MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports / Centers for Disease Control. 1992; 41(RR-14):1-7.

Description:

Spina bifida and anencephaly are common and serious birth defects. Available evidence indicates that 0.4 mg (400 micrograms) per day of folic acid, one of the B vitamins, will reduce the number of cases of neural tube defects (NTDs). In order to redu...

Status:

current

File Type:

[PDF - 2.74 MB]
Maternal Use of Opioids During Pregnancy and Congenital Malformations: A Systematic Review

Personal Author:

Lind, Jennifer N.; Interrante, Julia D.; Ailes, Elizabeth C.; Gilboa, Suzanne M.; Khan, Sara; Frey, Meghan T.; Dawson, April L.; Honein, Margaret A.; Dowling, Nicole F.; Razzaghi, Hilda; Creanga, Andreea A.; Broussard, Cheryl S.;

Published:

Jun 2017

Source:

Pediatrics. 139(6).

Description:

CONTEXT : Opioid use and abuse have increased dramatically in recent years, particularly among women. : OBJECTIVES : We conducted a systematic review to evaluate the association between prenatal opioid use and congenital malformations. : DATA SOURCES...

Public Access
Available on:

June 01, 2018
Pregnancy termination following prenatal diagnosis of anencephaly or spina bifida: a systematic review of the literature

Personal Author:

Johnson, Candice Y.; Honein, Margaret A.; Flanders, W. Dana; Howards, Penelope P.; Oakley, Godfrey P.; Rasmussen, Sonja A.;

Published:

Oct 25 2012

Source:

Birth Defects Res A Clin Mol Teratol. 94(11):857-863.

Description:

Background : In regions where prenatal screening for anencephaly and spina bifida is widespread, many cases of these defects are prenatally diagnosed. The purpose of this study was to estimate the frequency of termination of pregnancy (TOP) following...

File Type:

[PDF - 169.37 KB]
The impact of folic acid intake on the association between diabetes, obesity, and spina bifida

Personal Author:

Parker, Samantha E; Yazdy, Mahsa M; Tinker, Sarah C; Mitchell, Allen A; Werler, Martha M;

Published:

May 24 2013

Source:

Am J Obstet Gynecol. 2013; 209(3):239.e1-239.e8.

Description:

Objective : To investigate the relationship between spina bifida and two established risk factors, pregestational diabetes and obesity, in both the presence and absence of the recommended daily folic acid intake in the periconceptional period. : Stud...

File Type:

[PDF - 213.94 KB]