Details:

Alternative Title:
Int J Environ Res Public Health
Publisher's site:
http://dx.doi.org/10.3390/ijerph10083263
Personal Author:
Benedum, Corey M. ; Yazdy, Mahsa M. ; Mitchell, Allen A. ; Werler, Martha M.
Benedum, Corey M. ; Yazdy, Mahsa M. ; Mitchell, Allen A. ; Werler, Martha M. Less -
Description:
This study was conducted to assess the association between the risks of spina bifida (SB) in relation to cigarette, alcohol, and caffeine consumption by women during the first month of pregnancy. Between 1988-2012, this multi-center case-control study interviewed mothers of 776 SB cases and 8,756 controls about pregnancy events and exposures. We evaluated cigarette smoking, frequency of alcohol drinking, and caffeine intake during the first lunar month of pregnancy in relation to SB risk. Logistic regression models were used to calculate adjusted odds ratios and 95% confidence intervals. Levels of cigarette smoking (1-9 and ≥10/day), alcohol intake (average ≥4 drinks/day) and caffeine intake (<1, 1, and ≥2 cups/day) were not likely to be associated with increased risk of SB. Further, results were similar among women who ingested less than the recommended amount of folic acid (400 μg/day).
Subject:
[+]
Adolescent
Adult
Alcohol Consumption
Alcohol Drinking
Article
Birth Defects
Caffeine
Caffeine Consumption
Case-Control Studies
Cigarettes
Coffee
Female
Folic Acid
Humans
Logistic Models
Pregnancy
Pregnancy Trimester, First
Risk Factors
Smoking
Spina Bifida
Spinal Dysraphism
Young Adult
Folic Acid

Source:
Int J Environ Res Public Health. 2013; 10(8):3263-3281.
Pubmed ID:
23917813
Pubmed Central ID:
PMC3774437
Document Type:
Journal Article
Funding:
DD000697/DD/NCBDD CDC HHS/United States
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:432c198a63a742ab734ecbae54fb6ef69dbdd88c50b1a2ca00aa44f5c8e001e2
File Type:

Supporting Files

• 	ijerph-10-03263-g001.gif	gif
  	ijerph-10-03263-g001.jpg	jpeg
  	ijerph-10-03263-i001.jpg	jpeg
  	ijerph-10-03263.nxml	txt
  	license.txt	txt

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