Characterization and Quantitation of Personal Exposures to Epoxy Paints in Construction Using a Combination of Novel Personal Samplers and Analytical Techniques: CIP-10MI, Liquid Chromatography-Tandem Mass Spectrometry and Ion Chromatography

Details

• Personal Author:
  Bello A ; Bello D ; Xue Y
• Description:
  Epoxy resins are extremely versatile products that are widely used in construction for coatings, adhesives, primers, and sealers. Occupational exposures to epoxies cause allergic contact dermatitis, occupational asthma, hypersensitivity pneumonitis (epoxy-resin lung) and acute decline in lung function. Despite these health concerns, there is a striking paucity of quantitative exposure data to epoxy resins in construction. The lack of practical analytical methods and suitable personal samplers for monitoring of reactive two-component epoxide systems in real-world applications has been an unmet challenge for decades. Sampling and analysis methods for epoxies should be able to collect the paint aerosols efficiently, stop polymerization reactions at the time of sample collection, and subsequently provide detailed multispecies characterization of epoxides, as well as the total epoxide group (TEG) content of a sample, to properly document the chemical composition of exposures to epoxide paints. In this work, we present the development and application of two new complementary quantitative analytical methods-liquid chromatography-tandem mass spectrometry with online ultraviolet detection and ion chromatography (IC)-for multispecies characterization of raw products, as well as inhalation and skin exposures to epoxy formulations in real-world construction applications. A novel personal sampler, CIP-10MI, was used for personal sampling of airborne epoxies. We report for the first time the results of personal inhalation and potential skin exposures to individual monomers and oligomers of bisphenol A diglycidyl ether (BADGE), as well as TEG, during metal structure coatings in construction; compare analytical results of the two analytical methods; and provide recommendations for method selection in future field studies. High inhalation and potential skin exposures to epoxies point to the need for interventions to reduce exposures among painters in construction. [Description provided by NIOSH]
• Subjects:
  Adhesives Asthma Asthma, Occupational Chromatography Construction Industry Environmental Exposure Epoxy Resins Hypersensitivity Lung Metals Occupational Health Paint Respiratory System Risk Assessment Risk Factors Safety Skin

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• Keywords:
  Allergic Reactions Analytical Methods Author Keywords: Bisphenol A Diglycidyl Ether BADGE CIP-10MI Construction Contact Dermatitis Dermal Exposures Epoxy Compounds Epoxy Paints Exposure Levels Hypersensitivity Pneumonitis Inhalation And Skin Exposures Ion Chromatography Liquid Chromatography-tandem Mass Spectrometry Lung Irritants Mass Spectrometry Metal Compounds Metallic Compounds Monitoring Systems Monomers Paints Resins Risk Factors Samplers Sealing Compounds Skin Exposure

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• ISSN:
  2398-7308
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Journal Article
• Place as Subject:
  Maryland ; Massachusetts ; OSHA Region 1 ; OSHA Region 3
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  65
• Issue:
  5
• NIOSHTIC Number:
  nn:20062290
• Citation:
  Ann Work Expo Health 2021 Jun; 65(5):539-553
• Contact Point Address:
  Dhimiter Bello, Department of Biomedical and Nutritional Sciences, Zuckerberg College of Health Sciences, University of Massachusetts Lowell, 883 Broadway Street, Dugan Hall 108C, Lowell, MA 01854
• Email:
  Dhimiter_Bello@uml.edu
• CAS Registry Number:
  Bisphenol A diglycidyl ether (CAS RN 1675-54-3)
• Federal Fiscal Year:
  2021
• NORA Priority Area:
  Construction
• Performing Organization:
  CPWR - The Center for Construction Research and Training, Silver Spring, Maryland
• Peer Reviewed:
  True
• Start Date:
  20090901
• Source Full Name:
  Annals of Work Exposures and Health
• End Date:
  20240831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:c82fa8c2faaf0ae9f570866badf129717f3300e701392a2820e62e278de51df4a7a57c427fd2014c6f3c86b1aee757c162aa3a28e45b1766787966cc70bf4343
• Download URL:
  https://stacks.cdc.gov/view/cdc/225570/cdc_225570_DS1.pdf
• File Type:
  [PDF - 943.30 KB ]