Occupational and Leisure-Time Physical Activity Differentially Predict 6-Year Incidence of Stroke and Transient Ischemic Attack in Women

Details

• Personal Author:
  Chen H ; Hall C ; Heck JE ; Krause N ; Ritz B ; Sandler DP
• Description:
  Objectives: Recent meta-analyses suggest a physical activity health paradox: high levels of occupational physical activity (OPA) increase cardiovascular disease (CVD) risk, while leisure-time physical activity (LTPA) decreases risk. However, studies of women and cerebrovascular disease are limited. This report examines physical activity effects on stroke and transient ischemic attack (TIA) among working women in the United States. Methods: OPA history, health status, and lifestyle were assessed by baseline interviews of 31 270 employed Sister Study participants aged 35-74 years. OPA was assessed at six intensity levels (lowest: "mostly sitting"); the highest three were combined as "high intensity work." Independent OPA and LTPA effects on 6-year cerebrovascular disease incidence were estimated in adjusted Cox proportional hazard models. Results: Stroke (N=441) and TIA (N=274) risk increased with more standing and higher intensity work at current and longest held job. Compared with mostly sitting, high intensity work at the current job increased TIA risk by 57% hazard ratio (HR) 1.57, 95% confidence interval (CI) 1.04-2.38. High intensity OPA at the longest held job increased risk for stroke by 44% (HR 1.44; 95% CI 1.08-1.93). Among women with CVD, sitting and standing equally, especially at the current job, increased risks up to two-fold (TIA HR 1.98, 95% CI 1.10-3.55) compared with mostly sitting at work. LTPA showed inverse associations. Conclusions: Higher intensity levels of OPA increased stroke and TIA risks, while LTPA decreased risks; results corroborate the physical activity health paradox for women and cerebrovascular disease. More standing at work increased cerebrovascular disease risks, especially for women with CVD. Description provided by NIOSH
• Subjects:
  • Cardiovascular Diseases
  • Cardiovascular System
  • Cohort Studies
  • Epidemiology
  • Occupational Health
  • Risk Assessment
  • Risk Factors
  • Safety
  • Women
• Keywords:
  • Cardiovascular disease
  • Physical exercise
  • Activity levels
  • Women
  • Ischemic stroke
  • Cohort studies
  • Epidemiology
  • Occupations
  • Risk factors
  • Author Keywords: cerebrovascular disease
  More +
• ISSN:
  0355-3140
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  California ; Michigan ; North Carolina ; OSHA Region 4 ; OSHA Region 5 ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  267-279
• Volume:
  45
• Issue:
  3
• NIOSHTIC Number:
  nn:20061848
• Citation:
  Scand J Work Environ Health 2019 May; 45(3):267-279
• Contact Point Address:
  Niklas Krause, MD, MPH, PhD, Fielding School of Public Health, Director, Southern California NIOSH Education and Research Center, University of California Los Angeles, Box 95-1772; 56-071 CHS, 650 Charles E. Young Drive South, Los Angeles, CA 90095-1772
• Email:
  niklaskrause@ucla.edu
• Federal Fiscal Year:
  2019
• Performing Organization:
  University of California Los Angeles
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Scandinavian Journal of Work, Environment & Health
• End Date:
  20270630
• Download URL:
  https://stacks.cdc.gov/view/cdc/225212/cdc_225212_DS1.pdf
• File Type:
  [PDF - 488.17 KB]
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:ba10eab2f40630d674cfff9d77449003aa61a9dfa56e140dd7fe9e0ca4a8ca042c32972dacab45d1486982ebf33038d01881876bf464d36244efda1cb05716f5