Occupational Respiratory and Skin Diseases Among Workers Exposed to Metalworking Fluids

Details

• Personal Author:
  Grimes, George R. ; Nett, Randall J. ; Stanton M ; Grimes, George R. ; Nett, Randall J. ; Stanton M
• Description:
  Purpose of review: To examine respiratory and skin diseases that occur among workers exposed to metalworking fluids (MWFs) used during machining processes. Recent findings: Five cases of a severe and previously unrecognized lung disease characterized by B-cell bronchiolitis and alveolar ductitis with emphysema (BADE) were identified among workers at a machining facility that used MWFs, although MWF exposure could not be confirmed as the etiology. In the United Kingdom, MWF is now the predominant cause of occupational hypersensitivity pneumonitis (HP). Under continuous conditions associated with respiratory disease outbreaks, over a working lifetime of 45 years, workers exposed to MWF at 0.1mg/m3 are estimated to have a 45.3% risk of acquiring HP or occupational asthma under outbreak conditions and a 3.0% risk assuming outbreak conditions exist in 5% of MWF environments. In addition to respiratory outcomes, skin diseases such as allergic and irritant contact dermatitis persist as frequent causes of occupational disease following MWF exposure. Summary: Healthcare providers need to consider MWF exposure as a potential cause for work-related respiratory and skin diseases. Additional work is necessary to more definitively characterize any potential association between MWF exposures and BADE. Medical surveillance should be implemented for workers regularly exposed to MWF. [Description provided by NIOSH]
• Subjects:
  Alveolitis, Extrinsic Allergic Asthma Asthma, Occupational Environmental Exposure Health Care Facilities Workforce And Services Hypersensitivity Lung Lung Diseases Manufacturing And Industrial Facilities Occupational Health Respiratory System Respiratory Tract Diseases Risk Assessment Risk Factors Safety Skin Skin Diseases Workplace

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• Keywords:
  Author Keywords: B-cell Bronchiolitis And Alveolar Ductitis With Emphysema Bronchial Asthma Bronchiolitis Contact Dermatitis Dermatitis Etiology Exposure Levels Hypersensitivity Pneumonitis Lung Disease Lung Disorders Machine Operation Medical Monitoring Metalworking Fluids MWFs Pneumonitis Pulmonary System Disorders Respiratory Diseases Respiratory System Disorders Risk Factors Skin Diseases Skin Irritants Statistical Analysis Surveillance Work-related Asthma Work Environment Workers

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• ISSN:
  1528-4050
• Document Type:
  Text
• Genre:
  Journal Article ; Journal Article
• Place as Subject:
  Ohio ; OSHA Region 3 ; OSHA Region 5 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH) ; National Institute for Occupational Safety and Health (NIOSH)
• Division:
  RHD - Respiratory Health Division ; DFSE - Division of Field Studies and Engineering ; RHD - Respiratory Health Division ; DFSE - Division of Field Studies and Engineering
• Topic:
  Workplace Safety & Health ; Workplace Safety & Health
• Location:
  North America ; North America
• Pages in Document:
  121-127
• Volume:
  21
• Issue:
  2
• NIOSHTIC Number:
  nn:20061781
• Citation:
  Curr Opin Allergy Clin Immunol 2021 Apr; 21(2):121-127
• Contact Point Address:
  Randall J. Nett, MD, MPH, National Institute for Occupational Safety and Health (NIOSH), 1000 Frederick Lane, MS-2800, Morgantown, West Virginia 26508
• Email:
  gge5@cdc.gov
• Federal Fiscal Year:
  2021
• NORA Priority Area:
  Services ; Services
• Peer Reviewed:
  True
• Source Full Name:
  Current Opinion in Allergy and Clinical Immunology
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:538c24f5e9cbee19eff76afe3b51ee6783e027000848a9ffd8dd2a11449e3e801fcfb23a4c37fc0761ffbecf204cf98357bd547f48a5696295a4f0d829e6458f
• Download URL:
  https://stacks.cdc.gov/view/cdc/225170/cdc_225170_DS1.pdf
• File Type:
  [PDF - 384.78 KB ]