Assessment of Triphenyl Phosphate (TPhP) Exposure to Nail Salon Workers by Air, Hand Wipe, and Urine Analysis

Details

• Personal Author:
  Calafat, Antonia M. ; Chen I-C ; Estill, Cheryl F. ; Jayatilaka N ; La Guardia MJ ; Mayer A ; Ospina, Maria ; Slone J ; Zhou M
• Description:
  Triphenyl phosphate (TPP or TPhP) is commonly used as an additive plasticizer or organophosphate flame retardant (OPFR) in consumer products including nail polish. We evaluated exposure to TPhP from 12 nail salon technicians working at four nail salons located in California over a period of two work days. Bulk samples of 15 nail polishes and other nail products were collected. Study participants also provided two personal air samples, two hand wipe samples (pre- and post-shift on day two), and two urine samples (pre-shift day one and post-shift day two). The geometric mean (GM) of TPhP air sampling concentrations was 7.39 ng/m3. Post-shift TPhP hand wipe concentrations (GM 1.35 ug/sample) were significantly higher (p = 0.024) than pre-shift hand wipe concentrations (GM 0.29 ug/sample). Diphenyl phosphate (DPP or DPhP), a urinary metabolite of TPhP used in this study as a biomarker of exposure, was detected in all post-shift urine samples and 75% of urine pre-shift samples. DPhP post-shift concentrations (GM 1.35 ug/g creatinine) were significantly higher than pre-shift concentrations (GM 0.84 ug/g creatinine; p = 0.012). In addition, DPhP post-shift concentrations were correlated with TPhP post-shift hand wipe concentrations, suggesting dermal contact may be a relevant exposure pathway for nail salon workers. [Description provided by NIOSH]
• Subjects:
  Biomarkers Energy Metabolism Environmental Monitoring Occupational Health Plastics Safety Skin Urine
• Keywords:
  Air Samples Author Keywords: Flame Retardants Dermal Exposures Exposure Assessment Flame Retardants Hair Salons Metabolites Nail Salon Workers Nail Technicians OPFRs Organophosphate Flame Retardants Plasticizers Sampling TPHP Triphenyl Phosphate Urinalysis

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• ISSN:
  1438-4639
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Georgia ; North Carolina ; Ohio ; OSHA Region 3 ; OSHA Region 4 ; OSHA Region 5 ; Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DFSE - Division of Field Studies and Engineering
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  231
• NIOSHTIC Number:
  nn:20061228
• Citation:
  Int J Hyg Environ Health 2021 Jan; 231:113630
• Contact Point Address:
  Alexander Mayer, Division of Field Studies and Engineering, National Institute for Occupational Safety and Health, 1090 Tusculum Ave, MS R-14, Cincinnati, OH 45226, USA
• Email:
  Nru1@cdc.gov
• CAS Registry Number:
  Diphenyl phosphate (CAS RN 838-85-7) ; Triphenyl phosphate (CAS RN 115-86-6)
• Federal Fiscal Year:
  2021
• Peer Reviewed:
  True
• Source Full Name:
  International Journal of Hygiene and Environmental Health
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:edcee872606c2721bf293decd08fab189649adb9d16ba8c7f9d3c185ec3f99a6cbd26f50e515311d50c542531b43bb6ab46699dd828ef279abecc389cc158e43
• Download URL:
  https://stacks.cdc.gov/view/cdc/224835/cdc_224835_DS1.pdf
• File Type:
  [PDF - 1.14 MB ]