Factors Related to Thickness of Melanoma: Multifactorial Analysis off Variables Correlated with Thickness of Superficial Spreading Malignant Melanoma in Man

Details

• Personal Author:
  Bart RS ; Esrig B ; Friedman RJ ; Harris MN ; Hennessey P ; Kopf AW ; Mintzis MM ; Ragaz A ; Rigel D ; Trau H
• Description:
  Computer analyses to identify correlations between thickness of primary superficial spreading malignant melanoma and eighteen variables previously reported to be related to prognosis were performed on a series of malignant melanomas. The variables that showed statistically significant (≤0.05) direct relationships to thickness were level (Clark), elevation of lesion, age of patient, least and greatest diameters of lesion, history of bleeding, ulceration, clinical and histologic stage, anatomic location, pedunculation, and satellitosis. The variables that did not correlate with thickness were clinical diagnosis of regional lymphadenopathy, in-transit metastasis, duration of lesion, sex, history of a previous malignant melanoma, and history of a pre-existing lesion at the site of the development of melanoma. Multiple regression analysis of the factors that showed statistically significant correlation with thickness of the primary lesion revealed a subset of six dominant variables that were most predictive of thickness, namely, level, elevation, largest diameter of lesion, ulceration, histologic stage, and age of the patient. [Description provided by NIOSH]
• Subjects:
  Age Factors Neoplasms Occupational Health Risk Assessment Risk Factors Safety Skin Skin Diseases
• Keywords:
  Age Factors Cancer Malignant Neoplasms Risk Factors Skin Cancer Skin Lesions
• ISSN:
  0148-0812
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  7
• Issue:
  8
• NIOSHTIC Number:
  nn:20061148
• Citation:
  J Dermatol Surg Oncol 1981 Aug; 7(8):645-650
• Contact Point Address:
  Alfred W. Kopf, M.D., Skin and Cancer Unit, 562 First Avenue, New York, NY 10016
• Federal Fiscal Year:
  1981
• Performing Organization:
  New York University, New York, New York
• Peer Reviewed:
  True
• Start Date:
  19790401
• Source Full Name:
  The Journal of Dermatologic Surgery and Oncology
• End Date:
  19820331
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:5f3e48be35f56486271a4f5baf09bc740e67154d12df161432dfbd55e14988f175efd8f3ca6749babe28f8388fe150dc72c81ce61f67dd0165da226376c5b448
• Download URL:
  https://stacks.cdc.gov/view/cdc/224789/cdc_224789_DS1.pdf
• File Type:
  [PDF - 1.16 MB ]