Primary Melanoma Thickness Correlated with Regional Lymph Node Metastases

Details

• Personal Author:
  Dubin N ; Harris MN ; Hidalgo D ; Roses DF ; Valensi QJ
• Description:
  We studied 119 patients with stage I primary cutaneous malignant melanoma, who were undergoing regional lymph node dissection, to determine the relationship of lymph node metastases to thickness of the primary lesion. The lymph nodes in the dissection specimen were each evaluated by serial sections. None of the patients with lesions less than 1.0 mm thick had nodal micrometastases. When lesions exceeded 1.0 mm in thickness, there was no appreciable increase in the incidence of nodal metastases until a thickness greater than 4.0 mm was reached, in which cases the incidence of metastases was 50%. Predictive variables were determined by multiple logistic regression analysis. Only lesions that were at least 4.0 mm thick and were not located on the upper extremities were significant predictors of lymph node metastases; within this category there was a 64% incidence of lymph node metastases. [Description provided by NIOSH]
• Subjects:
  Lymphatic System Neoplasms Occupational Health Pathology Safety Skin Skin Diseases
• Keywords:
  Cancer Dermatology Lymph Nodes Malignant Neoplasms Metastatic Disease Skin Cancer Skin Lesions
• ISSN:
  0004-0010
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  117
• Issue:
  7
• NIOSHTIC Number:
  nn:20061103
• Citation:
  Arch Surg 1982 Jul; 117(7):921-923
• Contact Point Address:
  Dr. Roses, NYU Medical Center, 530 First Ave, New York, NY 10016
• Federal Fiscal Year:
  1982
• Performing Organization:
  New York University, New York, New York
• Peer Reviewed:
  True
• Start Date:
  19790401
• Source Full Name:
  Archives of Surgery
• End Date:
  19820331
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:8eacd4175f6f747b8e6b8f65a6d02b6880b2526a5d553ada4d9897604f4811763c017f5f8abb16d9a61f52ac1c5415217bb241a168f4713ff27907d0bd1b7152
• Download URL:
  https://stacks.cdc.gov/view/cdc/224768/cdc_224768_DS1.pdf
• File Type:
  [PDF - 347.60 KB ]