Spirometric Abnormalities and Lung Function Decline in Current and Former Microwave Popcorn and Current Flavoring Manufacturing Workers

Details

• Personal Author:
  Bailey, Rachel L. ; Cox-Ganser, Jean M. ; Cummings, Kristin J. ; Fechter-Leggett, Ethan D. ; Fedan, Kathleen B. ; White, Sandra K.
• Description:
  Objective: The aim of this study was to compare spirometry results in microwave popcorn and flavoring manufacturing workers. Methods: We used NIOSH data on current and former microwave popcorn workers (MPWs) and surveillance data on flavoring manufacturing workers (FMWs). Results: Former MPW had higher prevalence of mixed and high severity abnormalities, some had excessive lung function drops. Current MPW had lowest occurrence of excessive lung function drops. FMW with excessive drops and spirometric abnormalities at last test had developed a restrictive pattern. Spirometric abnormalities and excessive drops were associated with work-related factors. Conclusion: There was evidence of a healthy worker survivor effect in MPW. Importantly, removal from exposure did not always stabilize lung function decline indicating a need for continued monitoring. The development of a restrictive pattern should raise the level of suspicion for possible work-related disease in flavoring-exposed workers. Description provided by NIOSH
• Subjects:
  • Diacetyl
  • Environmental Exposure
  • Flavoring Agents
  • Lung
  • Lung Diseases
  • Manufacturing and Industrial Facilities
  • Occupational Health
  • Respiratory Function Tests
  • Respiratory System
  • Respiratory Tract Diseases
  More +
• Keywords:
  • Lung
  • Lung disorders
  • Respiratory system disorders
  • Pulmonary system disorders
  • Food additives
  • Flavorings
  • Diacetyl
  • Spirometry
  • Manufacturing
  • Workers
  More +
• ISSN:
  1076-2752
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  California ; OSHA Region 3 ; OSHA Region 8 ; OSHA Region 9 ; Utah ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  RHD - Respiratory Health Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  412-419
• Volume:
  62
• Issue:
  6
• NIOSHTIC Number:
  nn:20059924
• Citation:
  J Occup Environ Med 2020 Jun; 62(6):412-419
• Contact Point Address:
  Jean M. Cox-Ganser, PhD, 1095 Willowdale Road, Morgantown, WV 26505
• CAS Registry Number:
  • Butanedione (CAS RN 431-03-8)
• Federal Fiscal Year:
  2020
• NORA Priority Area:
  Manufacturing
• Peer Reviewed:
  True
• Source Full Name:
  Journal of Occupational and Environmental Medicine
• Download URL:
  https://stacks.cdc.gov/view/cdc/223978/cdc_223978_DS1.pdf
• File Type:
  [PDF - 215.00 KB]
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:507dc5fe23a20b07df71a42041c84bc0dc5050b2d56bda862369f64227fd8322e85c98b3760e46ba8e868ac9fb4d52728f0c0cf02e29f1a68a2d5cf6ec2c58e6