Symptomatic Responses to Low-Level Occupational and Environmental Exposures

Details

• Personal Author:
  Linde B ; Redlich CA
• Description:
  There are individuals who experience symptom responses at low levels of exposure (i.e. exposures at levels below those generally considered toxic). Through enigmatic and at times controversial, there is a basis of plausibility for these reactions. For any given exposure, interindividual variability in responsiveness exists, such that there is a proportion of individuals who demonstrate heightened responses compared to others. In addition, there is an increasing awareness that mixed exposures can produce different dose-response curves than to the isolated single exposures that have historically been the focus of laboratory investigation and regulatory efforts. Despite the centrality of the dose-response relationship to the fields of toxicology, industrial hygiene, and occupational health, certain human responses and diseases are not easily explained by traditional dose-response relationships. [Description provided by NIOSH]
• Subjects:
  Environmental Exposure Hazardous Substances Laboratories Occupational Exposure Occupational Health Risk Assessment Risk Factors Safety Toxicology
• Keywords:
  Diseases Dose Response Environmental Exposure Exposure Levels Humans Industrial Hygiene Occupational Exposure Occupational Health Regulations Risk Factors Toxins

  More +
• ISBN:
  9781119791515
• Publisher:
  John Wiley & Sons, Inc.
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Book
• Place as Subject:
  Connecticut ; New Jersey ; OSHA Region 1 ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  241-254
• Volume:
  1
• NIOSHTIC Number:
  nn:20064640
• Citation:
  Patty's industrial hygiene, seventh edition. Volume 1: hazard recognition. Cohrssen B ed. Hoboken, NJ: John Wiley & Sons, Inc., 2021 Mar; 1(Pt 2):241-254
• Editor(s):
  Cohrssen B
• Federal Fiscal Year:
  2021
• Performing Organization:
  Yale University School of Medicine
• Peer Reviewed:
  False
• Part Number:
  2
• Start Date:
  20010701
• Source Full Name:
  Patty's industrial hygiene, seventh edition. Volume 1: hazard recognition
• End Date:
  20260630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:6017b0cfc8d1a733f2453ecaf058bbdc41985343dd7f15070d7d887cfee9caa4779705caa5a18f5881899b9dbd6eb0164f524c884c08734dc623cd30704c41e4
• Download URL:
  https://stacks.cdc.gov/view/cdc/223068/cdc_223068_DS1.pdf
• File Type:
  [PDF - 1.84 MB ]