Occupational Radiation Exposure and Thyroid Cancer Incidence in a Cohort of U.S. Radiologic Technologists, 1983–2013

Details

• Personal Author:
  Alexander BH ; Doody MM ; Kitahara CM ; Linet MS ; Little MP ; Neta G ; Preston DL ; Sigurdson AJ ; Simon SL
• Description:
  Although childhood exposure to ionizing radiation is a well-established risk factor for thyroid cancer, the risk associated with adulthood exposure remains unclear. We prospectively examined the association between cumulative, low-to-moderate dose occupational radiation exposure to the thyroid and thyroid cancer incidence in the U.S. Radiologic Technologists cohort. The study included 89,897 members who completed at least two of four mailed questionnaires and were cancer-free at the time of the first questionnaire. Cumulative occupational thyroid radiation dose (mean = 57 mGy, range = 0-1,600 mGy) was estimated based on self-reported work histories, historical data and, during the years 1960-1997, 783,000 individual film badge measurements. During follow-up, we identified 476 thyroid cancer cases. We used Poisson regression to estimate excess relative risk of thyroid cancer per 100 milliGray (ERR/100 mGy) absorbed dose to the thyroid gland. After adjusting for attained age, sex, birth year, body mass index and pack-years smoked, we found no association between thyroid dose and thyroid cancer risk (ERR/100 mGy = -0.05, 95% CI <-0.10, 0.34). In this large cohort study of radiologic technologists, protracted, low-to-moderate dose ionizing radiation exposure to the thyroid gland in adulthood was not associated with an increased risk of thyroid cancer. [Description provided by NIOSH]
• Subjects:
  Cohort Studies Epidemiology Health Personnel Neoplasms Occupational Exposure Occupational Health Radiation Safety
• Keywords:
  Author Keywords: Thyroid Cancer Cancer Rates Cohort Studies Cohort Study Health Care Workers Ionizing Radiation Medical Personnel Occupational Exposure Radiation Exposure Radiologic Technologists Radiology Thyroid Gland Disorders

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• ISSN:
  0020-7136
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  California ; Maryland ; Minnesota ; OSHA Region 3 ; OSHA Region 5 ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  143
• Issue:
  9
• NIOSHTIC Number:
  nn:20064438
• Citation:
  Int J Cancer 2018 Nov; 143(9):2145-2149
• Contact Point Address:
  Cari M. Kitahara, PhD, MHS, National Cancer Institute, 9609 Medical Center Drive, Rm 7E-536, Bethesda, MD 20892, USA
• Email:
  kitaharac@mail.nih.gov
• Federal Fiscal Year:
  2019
• Performing Organization:
  University of Minnesota Twin Cities
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  International Journal of Cancer
• End Date:
  20250630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7528c3ad8a0f519e335ee7a1303b56b37ab9699a55389bff2532da3a917aca1802d4970644cdce2290cb1ce8321d8355c8190a8250da50bc9f1a9230eae63f7b
• Download URL:
  https://stacks.cdc.gov/view/cdc/222894/cdc_222894_DS1.pdf
• File Type:
  [PDF - 379.66 KB ]