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i

Expansion of the Performance Capabilities of the USF Inhalation Challenge Chamber



Details

  • Personal Author:
  • Description:
    Objective: This study enhances the capabilities of a whole-body human exposure chamber and determines the largest particle size that can be generated consistently. Once this size is determined, the inhalable and thoracic fractions of the dust cloud are determined. This chamber is located in the Breath Laboratory of the Sunshine ERC at the University of South Florida, College of Public Health. The chamber is Plexiglass, has a volume of 75 ft3, and is operated at a flow rate of 33.8 ft3/min. Both makeup and exhaust air are HEPA filtered. Methods: Previous work has been conducted with this chamber to generate respirable dust fractions only, using an elutriator to eliminate larger particles. A direct-reading instrument (TEOM) was used to determine particle concentration. In this work the generated thoracic dust fractions were sampled using gravimetric and direct-reading instruments. Results: Total dust concentrations in ug/m3 measured by the TEOM at various RPM settings of the Wright Dust Feeder were 110 + 2.8, 173 + 8.5, 398 + 20 and 550 + 17. Total dust concentrations as measured by gravimetric analysis, in ug/m3, at various RPM settings of the Wright Dust Feeder were 135 + 21, 200 + 35, 333 + 18 and 891 + 27. Similar results were found for the inhalable fraction and lower concentrations were found for the respirable fraction. Dust concentrations measured at different points within the chamber showed uniform distribution with variability less than 10%. The particle size distributions were consistent across the different RPM settings. Conclusion: By determining the largest particle size that can be consistently generated, future inhalation challenge studies using inhalable and thoracic-size particles will be possible with this chamber. [Description provided by NIOSH]
  • Subjects:
  • Keywords:
  • Publisher:
    University of South Florida (USF)
  • Document Type:
    Text
  • Funding:
    Grant
  • Genre:
    Abstract or Summary
  • Place as Subject:
  • CIO:
    National Institute for Occupational Safety and Health (NIOSH)
  • Topic:
    Workplace Safety & Health
  • Location:
    North America
  • Pages in Document:
    15
  • NIOSHTIC Number:
    nn:20064316
  • Citation:
    Sunshine ERC Research Poster Session/USF Health Research Day, February 20-22, 2014, Tampa, Florida. Tampa, FL: University of South Florida (USF), 2014 Feb; :15
  • Contact Point Address:
    Laura Riley, USF Sunshine ERC Industrial Hygiene Program
  • Federal Fiscal Year:
    2014
  • Performing Organization:
    Sunshine Education and Research Center, University of South Florida
  • Peer Reviewed:
    False
  • Start Date:
    20050701
  • Source Full Name:
    Sunshine ERC Research Poster Session/USF Health Research Day, February 20-22, 2014, Tampa, Florida
  • End Date:
    20290630
  • Collection(s):
  • Main Document Checksum:
    urn:sha-512:e8cd471053fac136138e78c150711daeabf9fad19c77958e5ed1183935ae1334fadd28d275f2b507cc966ecc76ff39ac21144a80d08437cdefb799063d3c222d
  • Download URL:
  • File Type:
    Filetype[PDF - 183.85 KB ]
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