Association of Amiodarone Use with Acute Pancreatitis in Patients with Atrial Fibrillation: A Nested Case-Control Study

Details

• Personal Author:
  Alonso A ; Chen LY ; Konety S ; Lutsey PL ; MacLehose RF
• Description:
  Amiodarone hydrochloride is an antiarrhythmic drug frequently used in the treatment of atrial fibrillation (AF). Isolated reports have suggested that use of amiodarone may cause acute pancreatitis. To our knowledge, this potential adverse effect of amiodarone has not been explored in large studies. We assessed whether use of amiodarone or other antiarrhythmic drugs indicated for AF management is associated with developing acute pancreatitis in a large US population. [Description provided by NIOSH]
• Subjects:
  Cardiovascular System Drug Therapy Occupational Health Safety
• Keywords:
  Cardiac Function Drug Therapy Heart Rate Medical Treatment Medicinal Chemicals Pancreas
• ISSN:
  2168-6106
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Case Studies
• Place as Subject:
  Minnesota ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  449-450
• Volume:
  175
• Issue:
  3
• NIOSHTIC Number:
  nn:20064266
• Citation:
  JAMA Intern Med 2015 Mar; 175(3):449-450
• Contact Point Address:
  Alvaro Alonso, MD, PhD, Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 S Second St, Ste 300, Minneapolis, MN 55454
• Email:
  alonso@umn.edu
• CAS Registry Number:
  Amiodarone (CAS RN 1951-25-3)
• Federal Fiscal Year:
  2015
• Performing Organization:
  University of Minnesota Twin Cities
• Peer Reviewed:
  False
• Start Date:
  20050701
• Source Full Name:
  JAMA Internal Medicine
• End Date:
  20250630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:4cf5682428763fae8771eb30849d8f7bbfed3ee14d87bcfec37716ea1807a0b98031936f4b6d7b8ba6bdd48b2dfa1ec0b1baa6a07a011f9af4c7e0b678593006
• Download URL:
  https://stacks.cdc.gov/view/cdc/222765/cdc_222765_DS1.pdf
• File Type:
  [PDF - 76.97 KB ]