Risk of Spontaneous Abortion in Women with Childhood Exposure to Parental Cigarette Smoke

Details

• Personal Author:
  Cramer DW ; Hauser R ; Meeker JD ; Missmer SA ; Vitonis AF
• Description:
  There is increasing concern over whether environmental exposures early in life may impact health in adulthood. Recent evidence suggests that prenatal or childhood exposure to cigarette smoke may result in poorer reproductive health later in life. Among 2,162 nonsmoking women recruited from three Boston, Massachusetts, clinics who underwent assisted reproductive treatments between 1994 and 2003, adjusted odds ratios for pregnancy outcomes in the initial treatment cycle were calculated in relation to self-reported childhood exposure to parental cigarette smoke. Women who reported having two parents who smoked during their childhood had increased odds of a spontaneous abortion compared with women reporting that neither parent smoked (adjusted odds ratio = 1.8, 95% confidence interval: 1.0, 3.0). A trend for increased risk was observed for women reporting that zero, one, or two parents smoked. In secondary analysis, the authors also found suggestive evidence for increased risk of failed embryo implantation among women reporting current secondhand tobacco smoke exposure. Future large studies of pregnancy loss are needed that can distinguish women's tobacco smoke exposure in childhood from that taking place in utero. [Description provided by NIOSH]
• Subjects:
  Environmental Exposure Occupational Health Pregnancy Risk Assessment Risk Factors Safety Smokers Urogenital System Women
• Keywords:
  Author Keywords: Spontaneous Abortion Children Cigarette Smoke Environmental Exposure Exposure Levels Health Effects Humans In Utero Exposure In Utero Study Maternal Exposure Parents Prenatal Exposure Reproductive Health Risk Risk Factors Secondhand Smoke Smoking Tobacco Smoke Pollution

  More +
• ISSN:
  0002-9262
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Massachusetts ; Michigan ; OSHA Region 1 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  166
• Issue:
  5
• NIOSHTIC Number:
  nn:20058447
• Citation:
  Am J Epidemiol 2007 Sep; 166(5):571-575
• Contact Point Address:
  John D Meeker, Department of Environmental Health Sciences, University of Michigan, Ann Arbor, MI 48109
• Email:
  meekerj@umich.edu
• Federal Fiscal Year:
  2007
• Performing Organization:
  Harvard School of Public Health
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  American Journal of Epidemiology
• End Date:
  20280630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:d9f759d7d814789159d85c1b49d0d545182d44149ecb018ce1746b909d630cb0f6ab1749a73154d189b25402860c5cf45f7033c48c32d7efcf926bf6ff04497e
• Download URL:
  https://stacks.cdc.gov/view/cdc/221539/cdc_221539_DS1.pdf
• File Type:
  [PDF - 95.90 KB ]