Hypersensitivity Pneumonitis from Pezizia Domiciliana: A Case of El Niño Lung

Details

• Personal Author:
  Dyer Z ; Harber P ; Kell DL ; Liebhaber MI ; Wright RS
• Description:
  A previously healthy woman developed severe dyspnea and was found to have restrictive lung disease and evidence of alveolitis. Open lung biopsy revealed extrinsic allergic alveolitis (hypersensitivity pneumonitis). The etiology was not initially apparent, but a home inspection showed an unusual mushroom growing in the patient's basement. Air sampling and serum precipitins against the fungal antigens confirmed that Pezizia domiciliana was the cause of the patient's hypersensitivity pneumonitis. This is the first described case of hypersensitivity pneumonitis cause by P. domiciliana. We speculate that unprecedented rainfall and flooding of the patient's basement as a result of El Niño rains produced ideal factors for the growth of this fungus. [Description provided by NIOSH]
• Subjects:
  Fungi Lung Lung Diseases Occupational Health Respiratory System Respiratory Tract Diseases Safety
• Keywords:
  Climatic Effects Climatic Factors Floods Fungal Infections Hypersensitivity Pneumonitis Indoor Environments Lung Disorders
• ISSN:
  1073-449X
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  California ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  160
• Issue:
  5
• NIOSHTIC Number:
  nn:20058304
• Citation:
  Am J Respir Crit Care Med 1999 Nov; 160(5)(Pt 1):1758-1761
• Contact Point Address:
  Robert S. Wright, M.D., Sansum-Santa Barbara Medical Foundation Clinic, Division of Pulmonary and Critical Care Medicine, P.O. Box 1200, Santa Barbara, CA 93102-1200
• Email:
  rwrightmd@earthlink.net
• Federal Fiscal Year:
  2000
• Performing Organization:
  University of California, School of Public Health, Los Angeles, California
• Peer Reviewed:
  True
• Part Number:
  1
• Start Date:
  19990701
• Source Full Name:
  American Journal of Respiratory and Critical Care Medicine
• End Date:
  20040630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:9df7c00461c5816c49c17ce974bb359482d3c9e67a80b05595e885b63ce9a8687cee98b0db559510b31c491e4728bb8a6d57e8c57de942d2feb0190689524416
• Download URL:
  https://stacks.cdc.gov/view/cdc/221431/cdc_221431_DS1.pdf
• File Type:
  [PDF - 603.29 KB ]