What are they? -- How do they work? -- What are the advantages of IGRAs? -- What are the disadvantages and limitations of IGRAs? -- What are the steps in administering an IGRA test? -- How do you interpret IGRA test results? -- Recommendations on when to use IGRA tests -- Can IGRAs be given to persons receiving vaccinations? -- Additional information.

Interferon-Gamma Release Assays (IGRAs) are whole-blood tests that can aid in diagnosing Mycobacterium tuberculosis infection. They do not help differentiate latent tuberculosis infection (LTBI) from tuberculosis disease. Two IGRAs that have been approved by the U.S. Food and Drug Administration (FDA) are commercially available in the U.S: QuantiFERON®-TB Gold In-Tube test (QFT-GIT); T-SPOT®.TB test (T-Spot).

Stephen B. Thacker CDC Library collection