Strategies for Setting Occupational Exposure Limits for Engineered Nanomaterials

Details

• Personal Author:
  Gordon T
• Description:
  An important mission of NIOSH-CDC is to generate scientific information to substantiate risk assessment and management of workplace hazards. Animal toxicology studies and a 'large number' of high throughput in vitro studies have consistently observed an association between exposure to engineered nanomaterials and adverse health effects. Less is known, however, about the dose-response or time course of response to inhaled nanomaterial and very little is known about the chronic effects of inhaled nanomaterials. While this information is being developed, there is little guidance to inform industrial hygienists how to efficiently set occupational exposure limits (OELs) for nanotechnology products currently being manufactured. Recently published papers indicate that scientists and industrial hygienists are struggling with this issue, yet none of the numerous national and international nanoparticle meetings held over the last 10 years, have focused on this issue. The topic for our conference on nanomaterial OELs arose because of this need and stakeholders and industrial hygienists suggested that developing a workshop that discussed establishing strategies for developing OELs for nanomaterials would be critical at this time. A diverse group of industry, academic, government, and non-government stakeholders was approached and all agreed to organize a workshop focused solely on setting OELs for nanomaterials. We recruited a focused group of speakers to meet and discuss strategies for setting OELs for nanomaterials. The individual critical issues were assigned to the first 1/2 day of the meeting and the remaining day and a half were devoted to presentations by individuals representing a diversity of stakeholders. Full participation of stakeholders, speakers, moderators, and audience occurred and appropriate time for questions, answers, and discussion was allocated for each session, although evaluation metrics suggested that more time should have been designated for discussion periods. Student scribes took notes throughout the meeting and an audio recording was taken and later transcribed. Both were used in the preparation of a manuscript that has been accepted for publication. In addition, powerpoint presentations for each speaker have been provided to the public via a website. [Description provided by NIOSH]
• Subjects:
  Occupational Health Respiratory System Safety Toxicology
• Keywords:
  Industrial Hygiene Inhalation Nanomaterials Nanotoxicology Occupational Exposure Limits OELs Risk Assessment
• Series:
  Grant Final Reports
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Final Grant Report
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  OEP - Office of Extramural Programs
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-6
• NIOSHTIC Number:
  nn:20056686
• Citation:
  Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, R13-OH-010337, 2013 Oct; :1-6
• Contact Point Address:
  Terry Gordon, PhD, NYU School of Medicine, 57 Old Forge Rd, Tuxedo, NY, 10987
• Email:
  terry.gordon@nyumc.org
• Federal Fiscal Year:
  2014
• NORA Priority Area:
  Manufacturing
• Performing Organization:
  New York University School of Medicine
• Peer Reviewed:
  False
• Start Date:
  20120701
• Source Full Name:
  National Institute for Occupational Safety and Health
• End Date:
  20130630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:d908945dd227eb8ec0708f5dfdf2e6177584ab2c27313096b990a462ac0eb297d4eb430f26a4fbb43659345e6baee0c605f192d381d4ec2a00a716f1a8ac6207
• Download URL:
  https://stacks.cdc.gov/view/cdc/218907/cdc_218907_DS1.pdf
• File Type:
  [PDF - 104.97 KB ]