Assessing the Impacts of Epidemiologic Biases in WTC Health Studies

Details

• Personal Author:
  Baron, Sherry L. ; Cifuentes M ; Jurek A ; Kim H ; Kriebel D ; Maldonaro G
• Description:
  This project aimed to assess the impact of epidemiologic biases in World Trade Center (WTC) health studies by identifying the presence of bias and subsequently quantifying and adjusting for the bias effects. Main methods used in the project are: 1) Quantitative bias evaluation with a systematic review of the literature related to WTC exposure and asthma incidence; 2) hypothetical bias assessment and adjustment; and 3) Heckman selection correction using empirical data collected from the WTC general responder cohort (GRC). The key findings from this study are: 1) Qualitative presence and the impact of potential biases in the context of WTC-related studies, and 2) a quantitative assessment of the presence of selection bias from existing literature and bias-corrected the association between WTC exposure and health outcome. This project introduced methods for bias identification and qualitative and quantitative adjustments in WTC cohorts. These methods will benefit the researchers in evaluating biases in their studies and in correcting the bias effect in causal inference. Our study findings can serve as a guideline to avoid biases from the study design phase in future disasters. [Description provided by NIOSH]
• Subjects:
  Asthma Emergency Responders Environmental Exposure Epidemiology Occupational Health Respiratory System Respiratory Tract Diseases Risk Assessment Risk Factors Safety September 11 Terrorist Attacks

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• Keywords:
  Bronchial Asthma Disaster Sites Exposure Levels First Responders Health Effects Risk Factors World Trade Center WTC
• Series:
  Grant Final Reports
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Final Cooperative Agreement Report
• Place as Subject:
  Massachusetts ; Minnesota ; New York ; OSHA Region 1 ; OSHA Region 2 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  OEP - Office of Extramural Programs
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-11
• NIOSHTIC Number:
  nn:20051059
• NTIS Accession Number:
  PB2018-100707
• Citation:
  Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, U01-OH-010730, 2017 Oct; :1-11
• Contact Point Address:
  Hyun Kim, ScD, Division of Environmental Health Sciences, School of Public Health, University of Minnesota, Twin Cities Campus, 420 Delaware Street SE, MMC 807, Room 1116 Mayo, Minneapolis, MN 55455
• Email:
  Kimx4804@umn.edu
• Federal Fiscal Year:
  2018
• Performing Organization:
  University of Minnesota - Minneapolis
• Peer Reviewed:
  False
• Start Date:
  20140701
• Source Full Name:
  National Institute for Occupational Safety and Health
• End Date:
  20170630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:dc45ff36ffc8e19761d8d4a01c07a88f3281dba701c72b9784395baf45baca791603e462de4ee88d8234039908bcd18c8908beec640ca1e00bf4fea283ad5445
• Download URL:
  https://stacks.cdc.gov/view/cdc/218680/cdc_218680_DS1.pdf
• File Type:
  [PDF - 126.39 KB ]