Understanding Vibration Injury
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2003/10/06
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Description:The present understanding of hand-arm vibration syndrome (HAVS) suffers from the lack of knowledge regarding the onset and progression of vibration injury of cells and tissues. Repeated injury generates neurovascular symptoms and, with longer exposures, matures into an irreversible disease. Without elucidating these basic mechanisms, the foundation is lacking on which to develop early detection and monitoring methods, countermeasure techniques and exposure guidelines for protecting workers. The current thinking for setting exposure guidelines relies on frequency weighted predictions, which progressively minimize the impact of frequencies above 16 Hz, even though recent reports from many laboratories, including ours, suggest this approach underestimates damage inflicted at higher frequencies. A large body of literature implies that vibration injury is frequency dependent but the studies fail to reach consensus on the relationship. There are many reasons for this controversy. The most blatant is an oversimplified view of how vibration parameters interact with the biology and a lack of knowledge about the underlying processes. Our studies have made significant advances in defining the early events by developing a rat tail vibration model to invoke vibration injury of arteries and nerves, which are similar in size and structure to the digital arteries and nerves in the human hand. Exploiting this model has provided inroads to understanding the earliest cell and tissue damage and its relationship to the vibration parameters of frequency, amplitude, acceleration and duration. [Description provided by NIOSH]
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Pages in Document:1-7
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NIOSHTIC Number:nn:20023815
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NTIS Accession Number:PB2004-104818
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Citation:Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, R01-OH-003493, 2003 Oct; :1-7
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Federal Fiscal Year:2004
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Performing Organization:Medical College of Wisconsin, Milwaukee, Wisconsin
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Peer Reviewed:False
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Start Date:19990901
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Source Full Name:National Institute for Occupational Safety and Health
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End Date:20160831
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Main Document Checksum:urn:sha-512:2d520be38095688351811a58a8fc0713ca6145b9f5cc594967bcd0eb538825898b30478942758f83b82472a417fe8cf13818483259c1fa5adb106f392ed00c5d
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