Lung Disease in Chinese Textile Workers

Details

• Personal Author:
  Christiani, David C.
• Description:
  The relationship between long term exposure to cotton dust and associated gram negative bacterial endotoxin on lung function was investigated in an 11 year prospective study of cotton textile workers in Shanghai, China. Workers at a nearby silk thread manufacturing mill served as a referent population. The cotton workers had a larger loss of lung function as measured by forced expiratory volume in 1 second (FEV1) during the first 5 years of the study than in the second 6 years. The average decline among silk workers was slightly higher in the first period, but was more consistent. Cumulative dust but not endotoxin was associated with an 11 year loss of FEV1 after adjustment for appropriate confounders when cumulative exposure to dust and endotoxin were estimated and retired workers included in the testing. No evidence was found for interaction between smoking and cumulative dust or cumulative endotoxin exposure in these models. Results suggest that the cotton dust is a relatively potent cause of chronic airflow limitation independent of associated endotoxins. [Description provided by NIOSH]
• Subjects:
  Dust Gossypium Lung Manufacturing And Industrial Facilities Occupational Exposure Occupational Health Respiratory System Respiratory Tract Diseases Safety Textile Industry
• Keywords:
  Cotton-dust Cotton-mill-workers Dust-exposure NIOSH-Grant Occupational-exposure Plant-dusts Pulmonary-function Pulmonary-system-disorders Textiles-industry
• Series:
  Grant Final Reports
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Final Grant Report
• Place as Subject:
  Massachusetts ; OSHA Region 1
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  OEP - Office of Extramural Programs
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-21
• NIOSHTIC Number:
  nn:00235386
• NTIS Accession Number:
  PB97-151773
• Citation:
  Department of Environmental Health, School of Public Health, Harvard University, Boston, Massachusetts 1995 Oct; :1-21
• Contact Point Address:
  Environmental Sci & Physiology Harvard School of Public Hlth 665 Huntington Ave Boston, MA 02115
• Federal Fiscal Year:
  1996
• Performing Organization:
  Harvard University
• Peer Reviewed:
  False
• Start Date:
  19870701
• Source Full Name:
  Department of Environmental Health, School of Public Health, Harvard University, Boston, Massachusetts
• End Date:
  20220831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:a0f198695a0a3858c94fd6f8841879e068fb97af2369f66c830eefd45317f73e338fbe01d87345e7182b53f3fac44b565a199e290756077f7e8250643f6990dd
• Download URL:
  https://stacks.cdc.gov/view/cdc/217895/cdc_217895_DS1.pdf
• File Type:
  [PDF - 1.05 MB ]