Effects of 27 MHz Radiation on Somatic and Germ Cells

Details

• Personal Author:
  Cleary SF
• Description:
  A study was made of the dose dependence of effects of 27 and 2450 megahertz (MHz) continuous wave (CW) and pulse modulated (PM) radiation exposure of normal resting peripheral human lymphocytes, human glioma (LN71), HeLa, and Chinese-hamster-ovary (CHO) cells. Direct radiation effects on mouse germ cells were also investigated. Effects of high frequency electromagnetic radiation (EMR) on lymphocyte and glioma mitogenesis and the CHO cell cycle in-vitro provide evidence of direct dose or dose rate dependent alteration of a highly physiologically significant cellular endpoint. Although in- vitro data cannot be extrapolated directly to in-vivo responses, the experimental conditions of these in-vitro studies suggest that qualitatively similar effects may be induced by in-vivo exposure to electromagnetic fields of these frequencies. The author concludes that physiologically significant cellular alterations are induced by 27 and 2450MHz CW and PM radiation exposure under conditions that do not involve heating. The author suggests that the adequacy of radiofrequency occupational exposure guidelines that suggest that health effects are attributable to radiation induced tissue heating must be questioned. [Description provided by NIOSH]
• Subjects:
  Electromagnetic Phenomena Occupational Health Radiation Safety Urogenital Diseases Urogenital System
• Keywords:
  Cell-function Electromagnetic-fields In-vitro-studies Mammalian-cells NIOSH-Grant Nonionizing-radiation Radiation-effects Radiation-exposure Reproductive-hazards Reproductive-system-disorders
• Series:
  Grant Final Reports
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Final Grant Report
• Place as Subject:
  OSHA Region 3 ; Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  OEP - Office of Extramural Programs
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-8
• NIOSHTIC Number:
  nn:00201860
• NTIS Accession Number:
  PB92-124007
• Citation:
  Department of Physiology, Medical College of Virginia, Virginia Commonwealth University 1991 Jan; :1-8
• Contact Point Address:
  Physiology and Biophysics Medical College of Virginia Box 694, Mcv Station Richmond, VA 23298
• Federal Fiscal Year:
  1991
• NORA Priority Area:
  Disease and Injury: Fertility and Pregnancy Abnormalities
• Performing Organization:
  Virginia Commonwealth University, Richmond, Virginia
• Peer Reviewed:
  False
• Start Date:
  19850927
• Source Full Name:
  Department of Physiology, Medical College of Virginia, Virginia Commonwealth University
• End Date:
  19930929
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:f2ba912450351bb05020be03992e9813b3c06b30c50477637fabfc53f8fa633969d4a652e953c1a93fafabb033faf473d0d8e76627f0bf33ae3d835f0b922818
• Download URL:
  https://stacks.cdc.gov/view/cdc/217811/cdc_217811_DS1.pdf
• File Type:
  [PDF - 584.54 KB ]