The Association Between Health Conditions in World Trade Center Responders and Sleep-Related Quality of Life and Sleep Complaints

Details

• Personal Author:
  Ayappa I ; Bagchi N ; Black K ; Chen Y ; Lu S-E ; Rapoport DM ; Sanders H ; Sunderram J ; Twumasi A
• Description:
  Background: World Trade Center (WTC) dust-exposed subjects have multiple comorbidities that affect sleep. These include obstructive sleep apnea (OSA), chronic rhinosinusitis (CRS), gastroesophageal-reflux disorder (GERD) and post-traumatic stress disorder (PTSD). We examined the impact of these conditions to sleep-related outcomes. Methods: Demographics, co-morbidities and symptoms were obtained from 626 WTC (109F/517M), 33-87years, BMI = 29.96 +/- 5.53 kg/m2) subjects. OSA diagnosis was from a 2-night home sleep test (ARESTM). Subjective sleep quality, sleep-related quality of life (QOL, Functional Outcomes of Sleep Questionnaire), excessive daytime sleepiness (Epworth Sleepiness Scale), sleep duration and sleep onset and maintenance complaints were assessed. Results: Poor sleep quality and complaints were reported by 19-70% of subjects and average sleep duration was 6.4 h. 74.8% of subjects had OSA. OSA diagnosis/severity was not associated with any sleep-related outcomes. Sleep duration was lower in subjects with all conditions (p < 0.05) except OSA. CRS was a significant risk factor for poor sleep-related QOL, sleepiness, sleep quality and insomnia; PTSD for poor sleep-related QOL and insomnia; GERD for poor sleep quality. These associations remained significant after adjustment for, age, BMI, gender, sleep duration and other comorbidities. Conclusions: Sleep complaints are common and related to several health conditions seen in WTC responders. Initial interventions in symptomatic patients with both OSA and comorbid conditions may need to be directed at sleep duration, insomnia or the comorbid condition itself, in combination with intervention for OSA. [Description provided by NIOSH]
• Subjects:
  Dust Emergency Responders Occupational Health Safety September 11 Terrorist Attacks
• Keywords:
  Author Keywords: Obstructive Sleep Apnea Chronic Sinusitis Comorbid Insomnia Dust Exposure Emergency Responders First Responders Gastroesophageal Reflux Disease GERD Post-traumatic Stress Disorder PTSD Quality Of Life Sleep-related Quality Of Life Sleep Apnea Sleepiness World Trade Center WTC WTC Responders

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• ISSN:
  1660-4601
• Document Type:
  Text
• Funding:
  Cooperative Agreement ; Contract
• Genre:
  Journal Article
• Place as Subject:
  New Jersey ; New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  16
• Issue:
  7
• NIOSHTIC Number:
  nn:20055367
• Citation:
  Int J Environ Res Public Health 2019 Apr; 16(7):1229
• Contact Point Address:
  Indu Ayappa, Division of Pulmonary, Critical Care and Sleep Medicine Icahn School of Medicine at Mount Sinai, New York, NY 10029
• Email:
  indu.ayappa@mssm.edu
• Federal Fiscal Year:
  2019
• Performing Organization:
  RBHS-Robert Wood Johnson Medical School, Piscataway, New Jersey
• Peer Reviewed:
  True
• Start Date:
  20120901
• Source Full Name:
  International Journal of Environmental Research and Public Health
• End Date:
  20170831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:fa24348d7df704fb7fcb098c05fcdb7cc29ab075e569bd1ad178a70e41e359d8b77cf6fbb476e17ec2dc0ef5723f1bf69728f97755794bd4e1109a7478f14dca
• Download URL:
  https://stacks.cdc.gov/view/cdc/217688/cdc_217688_DS1.pdf
• File Type:
  [PDF - 661.79 KB ]