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Environmental Exposure History and Vulvodynia Risk: A Population-Based Study



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  • Personal Author:
  • Description:
    Background: Risk factors for vulvodynia continue to be elusive. We evaluated the association between past environmental exposures and the presence of vulvodynia. Materials and Methods: The history of 28 lifetime environmental exposures was queried in the longitudinal population-based Woman-to-Woman Health Study on the 24-month follow-up survey. Relationships between these and vulvodynia case status were assessed using multinomial logistic regression. Results: Overall, 1585 women completed the 24-month survey, the required covariate responses, and questions required for case status assessment. Screening positive as a vulvodynia case was associated with history of exposures to home-sprayed chemicals (insecticides, fungicides, herbicides-odds ratio [OR] 2.47, 95% confidence interval [CI] 1.71-3.58, p<0.0001), home rodent poison and mothballs (OR 1.62, 95% CI 1.25-2.09, p<0.001), working with solvents and paints (OR 2.49, 95% CI 1.68-3.70, p<0.0001), working as a housekeeper/maid (OR 2.07, 95% CI 1.42-3.00, p<0.0001), working as a manicurist/hairdresser (OR 2.00, 95% CI 1.14-3.53, p<0.05), and working at a dry cleaning facility (OR 2.13, 95% CI 1.08-4.19, p<0.05). When classified into nine individual environmental exposure categories and all included in the same model, significant associations remained for four categories (home-sprayed chemicals, home rodent poison or mothballs, paints and solvents, and working as a housekeeper). Conclusions: This preliminary evaluation suggests a positive association between vulvodynia and the reported history of exposures to a number of household and work-related environmental toxins. Further investigation of timing and dose of environmental exposures, relationship to clinical course, and treatment outcomes is warranted. [Description provided by NIOSH]
  • Subjects:
  • Keywords:
  • ISSN:
    1540-9996
  • Document Type:
    Text
  • Funding:
    Grant
  • Genre:
    Journal Article
  • Place as Subject:
  • CIO:
    National Institute for Occupational Safety and Health (NIOSH)
  • Topic:
    Workplace Safety & Health
  • Location:
    North America
  • Pages in Document:
    69-76
  • Volume:
    28
  • Issue:
    1
  • NIOSHTIC Number:
    nn:20055213
  • Citation:
    J Womens Health 2019 Jan; 28(1):69-76
  • Contact Point Address:
    Barbara D. Reed, MD, MSPH, Department of Family Medicine, University of Michigan, 1018 Fuller Street, Ann Arbor, MI 48104-1213
  • Email:
    barbr@umich.edu
  • Federal Fiscal Year:
    2019
  • Performing Organization:
    University of Michigan, Ann Arbor
  • Peer Reviewed:
    True
  • Start Date:
    20050701
  • Source Full Name:
    Journal of Women's Health
  • End Date:
    20280630
  • Collection(s):
  • Main Document Checksum:
    urn:sha-512:589ecefc7c5d1b785d5d4387faa133bbe3f3e8b7c2c0e58ff7928e2e14a165684f93dfe1fb78c380df13d870b0138782cf64688d15b06205b764a51b3dffd5a0
  • Download URL:
  • File Type:
    Filetype[PDF - 145.83 KB ]
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