Urinary Phthalate Metabolite Concentrations Among Custodians Using Green Cleaners

Details

• Personal Author:
  Cavallari J ; Cherniack, Martin G. ; Morse T ; Simcox NJ ; Wakai S ; Welsh L ; Westinghouse C
• Description:
  Background: Phthalates represent a class of ubiquitous chemicals that are commonly found in consumer and personal care products and used as plasticizers and stabilizers in building materials. DEHP, DBP, and MBzP are commonly found phthalates in cleaning products or materials used by custodians, who may represent a high-risk occupational group. This study characterizes the urinary phthalate metabolite concentrations among custodians as they transitioned from traditional cleaners to the use of green or Environmentally Preferable Products (EPP). Methods: Sixty-eight custodians provided four urine samples per shift (first void, before shift, end of shift and before bedtime). During each hour of the work shift, trained observers recorded cleaning tasks, and the type of product used (traditional or EPP). Five different phthalates metabolites MEHP, MMP, MBzP, MEP, MnBP corresponding to DEHP, DBP, BBP DEP, DBP were quantified in the urine using Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS). Results: Geometric mean (standard deviation) urinary levels MEHP, MPB and MBzP are 6.9 (3.3), 20 (3.2), 8.8 (2.6) ug/g, respectively. For MBZP, we observed significantly (p=0.001) higher levels among custodians using traditional cleaners >4hrs. Custodians with >4hrs traditional cleaners use had higher end of shift MBzP urinary levels (19.5 ug/g) as compared to custodians using EPPS (13.1 ug/g). We will report urinary metabolite levels among custodians using EPPs and traditional cleaners during different times of the shift. Conclusion: Our results suggest that different species of urinary phthalate metabolites measured in urine may be associated with occupational exposure. [Description provided by NIOSH]
• Subjects:
  Biomarkers Occupational Exposure Occupational Health Safety
• Keywords:
  Author Keywords: Occupational Health Cleaning Compounds Custodians Health Effects Occupational Exposure
• Publisher:
  American Public Health Association
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Proceedings
• Place as Subject:
  Connecticut ; OSHA Region 1 ; OSHA Region 10 ; Washington
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• NIOSHTIC Number:
  nn:20055066
• Citation:
  Think Global, Act Local: APHA 141st Annual Meeting and Exposition, November 2-6, 2013, Boston, Massachusetts. Washington, DC: American Public Health Association, 2013 Nov; :279092
• Email:
  nsimcox@u.washington.edu
• Federal Fiscal Year:
  2014
• NORA Priority Area:
  Services
• Performing Organization:
  University of Connecticut Schools of Medicine, Farmington
• Peer Reviewed:
  False
• Start Date:
  20090901
• Source Full Name:
  Think Global, Act Local: APHA 141st Annual Meeting and Exposition, November 2-6, 2013, Boston, Massachusetts
• End Date:
  20140831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:453ad91bd2b7122a05aea28a86c0b913705756d7f1803d6ec4611b922c6e0d27f855bc102f00807e83e5afab3e937320ae9e8a5303e29c683db371a5dd42b262
• Download URL:
  https://stacks.cdc.gov/view/cdc/217444/cdc_217444_DS1.pdf
• File Type:
  [PDF - 117.22 KB ]