Immunotoxicity of PFCs (perfluoroalkyl compounds) Found in Fire-Fighting Foams

Details

• Personal Author:
  Pecquet AM
• Description:
  This presentation has the following summary and conclusions: PFOA not highly toxic: Causes developmental malformations in zebrafish embryos; Potential window of susceptibility? PFOA suppresses the innate immune response: Reduces neutrophil recruitment to the inflammatory site up to 45%; Implications for reduced wound healing, increased infection. [Description provided by NIOSH]
• Subjects:
  Fires Immune System Occupational Health Safety
• Keywords:
  Cell Signaling Dose Response Exposure Assessment Fire Fighting Fire Retardants Immune Reaction Immunotoxins
• Publisher:
  University of Cincinnati
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Proceedings
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-14
• NIOSHTIC Number:
  nn:20054970 ; nn:20054971
• Citation:
  19th Annual Pilot Research Project Symposium, University of Cincinnati Education and Research Center, October 11-12, 2018, Cincinnati, Ohio. Cincinnati, OH: University of Cincinnati, 2018 Oct; :1-14
• Email:
  Pecqueam@mail.uc.edu
• CAS Registry Number:
  Perfluorooctanoic acid (CAS RN 335-67-1)
• Federal Fiscal Year:
  2019
• Performing Organization:
  University of Cincinnati
• Peer Reviewed:
  True
• Start Date:
  20050701
• End Date:
  20260630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:aa3e623ed56a694cc6cca1e006a59e26e15d442e6db30a5b4df61735d90c07771c609f786cdfc19685254fae5d991a5665b1322c45a77f7e85c8760c1f019c0a
• Download URL:
  https://stacks.cdc.gov/view/cdc/217377/cdc_217377_DS1.pdf
• File Type:
  [PDF - 833.19 KB ]