Work-Related Lung Cancer: The Practitioner’s Perspective

Details

• Personal Author:
  Howard J ; Weissman, David N.
• Description:
  Work exposures are well-known risk factors for lung cancer. A recent review noted that the International Agency for Research on Cancer (IARC) has found "sufficient evidence" that 19 occupational agents can cause lung cancer in humans (IARC Group 1). Two key factors affecting risk for work-related lung cancer are level of exposure to one or more occupational carcinogens and smoking history, with these two factors often having greater than additive effects. Primary prevention by reducing or eliminating causative exposures to occupational carcinogens and tobacco smoke is the best way to prevent the human and economic costs of work-related lung cancer. The National Institute for Occupational Safety and Health has published an updated Chemical Carcinogen Policy, including a new occupational exposure limit: the Risk Management Limit for Carcinogens, which generally will be set at a risk level of one excess cancer case per 10,000 workers in a 45-year working lifetime. ... With improved effectiveness data and technological advances such as blood biomarkers for lung cancer and ultra-low-dose CT, the practice of low-dose chest CT screening for work-related lung cancer undoubtedly will continue to evolve. Still, it is important never to forget that primary prevention of lung cancer - that is, preventing exposure to tobacco, occupational carcinogens, and other lung carcinogens - is the most effective type of prevention. [Description provided by NIOSH]
• Subjects:
  Biomarkers Carcinogens Decision Making Delivery Of Health Care Diagnosis Economics Environmental Exposure Hazardous Substances Health Personnel Lung Lung Diseases Neoplasms Occupational Exposure Occupational Health Radiography Respiratory System Respiratory Tract Diseases Risk Assessment Risk Factors Safety Smoke Smokers Tobacco Products Workplace

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• Keywords:
  Cancer Chemical Hazards Chest Radiography Cigarette Smoking Clinical Diagnosis Clinical Tests Costs Decision Making Diagnostic Techniques Disease Prevention Economic Impact Effectiveness Research Employee Exposure Exposure Levels Health Care Health Hazards Humans Lung Cancer Medical Care Medical Personnel Medical Screening Medical Services Nuclear Hazards Occupational Cancers Physicians Risk Factors Risk Management Screening Methods Screening Programs Smoking Synergistic Effects Tobacco Smoke Toxic Materials Work Environment

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• ISSN:
  0090-0036
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  District of Columbia ; OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  RHD - Respiratory Health Division ; OD - Office of the Director
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  108
• Issue:
  10
• NIOSHTIC Number:
  nn:20052986
• Citation:
  Am J Public Health 2018 Oct; 108(10):1290-1292
• Contact Point Address:
  John Howard, MD, National Institute for Occupational Safety and Health, 395 E St SW, Washington, DC 20201
• Email:
  zkz1@cdc.gov
• CAS Registry Number:
  Arsenic (CAS RN 7440-38-2) ; Asbestos (CAS RN 1332-21-4) ; Beryllium (CAS RN 7440-41-7) ; Cadmium (CAS RN 7440-43-9) ; Chloromethyl ether (CAS RN 542-88-1) ; Chloromethyl methyl ether (CAS RN 107-30-2) ; Chromium(6+) (CAS RN 18540-29-9) ; Nickel (CAS RN 7440-02-0) ; Plutonium (CAS RN 7440-07-5) ; Quartz (SiO2) (CAS RN 14808-60-7) ; Radon (CAS RN 10043-92-2) ; Sulfur mustard (CAS RN 505-60-2) ; Tobacco oil (CAS RN 8037-19-2)
• Federal Fiscal Year:
  2019
• Peer Reviewed:
  False
• Source Full Name:
  American Journal of Public Health
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:0172e9dd2a47b7fd99c5f55b7ff7261b128745514f17fcf07ac47fb728fb622b547239630b1c7873e1c9774da59ee9778b09c7e7b641c5d1d26de4d645065351
• Download URL:
  https://stacks.cdc.gov/view/cdc/215865/cdc_215865_DS1.pdf
• File Type:
  [PDF - 675.09 KB ]