Hemolytic Anemia Following Succimer Administration in a Glucose-6-Phosphate Dehydrogenase Deficient Patient

Details

• Personal Author:
  Frumkin H ; Gerr F ; Hodgins P
• Description:
  Because of its favorable side effects profile, the oral chelating agent dimercaptosuccinic acid is often used for treatment of lead intoxication. We report a case of a 45-year-old black male with glucose-6-phosphate dehydrogenase deficiency and a 17 year history of occupational lead exposure who developed hemolysis during treatment with dimercaptosuccinic acid for symptomatic lead intoxication. [Description provided by NIOSH]
• Subjects:
  Blood Chelating Agents Lead Lead Poisoning Occupational Exposure Occupational Health Poisoning Safety
• Keywords:
  Author Keywords: Dimercaptosuccinic Acid Chelates Chelating Agents Hemolysis Hemolytic Anemia Human Humans Lead Poisoning Lead Toxicity Occupational Exposure
• ISSN:
  0731-3810
• Document Type:
  Text
• Funding:
  Grant ; Cooperative Agreement
• Genre:
  Journal Article
• Place as Subject:
  Georgia ; OSHA Region 4
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  32
• Issue:
  5
• NIOSHTIC Number:
  nn:20057930
• Citation:
  J Toxicol Clin Toxicol 1994 Sep; 32(5):569-575
• Contact Point Address:
  Dr. Fredric Gerr, Division of Environmental and Occupational Health, Emory University School of Public Health, 1599 Clifton Road, Atlanta, GA 30329
• CAS Registry Number:
  Lead (CAS RN 7439-92-1)
• Federal Fiscal Year:
  1994
• Performing Organization:
  Emory University, Atlanta, Georgia
• Peer Reviewed:
  True
• Start Date:
  19920701
• Source Full Name:
  Journal of Toxicology: Clinical Toxicology
• End Date:
  19940630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:d9019333a7be1b7ec3738baac1c71ee00b1f347c44da55a032b7a57668bf5d2854b03d591399bb88593c67dc052652911fb136293ee148eddae4ee0a8f190a17
• Download URL:
  https://stacks.cdc.gov/view/cdc/215132/cdc_215132_DS1.pdf
• File Type:
  [PDF - 557.14 KB ]