Occupational Exposure to Dibutyl Phthalate Among Manicurists

Details

• Personal Author:
  Calafat, Antonia M. ; Duty SM ; Hauser R ; Kozaczka S ; Kwapniewski R ; Silva MJ
• Description:
  Objective: To measure manicurists' exposure to dibutyl phthalate (DBP) at work and to determine whether workplace characteristics influence this exposure. DBP is a reproductive and developmental toxicant in rats and is used in nail polish to hold color and prevent chipping. Methods: Pre- and postshift spot urine samples were collected from 40 manicurists. Linear regression compared the relationship between the log of the cross-shift differences in urinary phthalate monoester metabolite concentrations and use of workplace exposure control methods. Results: There was a statistically significant cross-shift increase of 17.4 ng/mL in the urinary concentration of mono-n-butyl phthalate, the major metabolite of DBP. Use of gloves reduced mono-nbutyl phthalate concentrations by 15.1 ng/mL below the preshift concentration compared with a 20.5 ng/mL increase if gloves were not worn. Conclusions: Manicurists are occupationally exposed to DBP and glove use may minimize this exposure. [Description provided by NIOSH]
• Subjects:
  Animals Energy Metabolism Environmental Exposure Hazardous Substances Laboratories Men Occupational Health Personal Protective Equipment Risk Assessment Risk Factors Safety Urine Women Workplace

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• Keywords:
  Dibutyl Phthalate Exposure Levels Gloves Humans Laboratory Animals Metabolites Risk Factors Sampling Toxins Urinalysis Work Environment Workers

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• ISSN:
  1076-2752
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Massachusetts ; OSHA Region 1
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  50
• Issue:
  6
• NIOSHTIC Number:
  nn:20057347
• Citation:
  J Occup Environ Med 2008 Jun; 50(6):705-711
• Contact Point Address:
  Susan Duty, RN, MSN, ScD, Department of Nursing, School for Health Studies, Simmons College, 300 The Fenway, Boston, MA 02115-5898
• Email:
  susan.duty.@simmons.edu
• CAS Registry Number:
  Dibutyl phthalate (CAS RN 84-74-2)
• Federal Fiscal Year:
  2008
• Performing Organization:
  Harvard School of Public Health
• Peer Reviewed:
  True
• Start Date:
  20030701
• Source Full Name:
  Journal of Occupational and Environmental Medicine
• End Date:
  20050630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:74c71c347bb79dca24cce1090d97a3eefe19e5055dfcd43585fd4e668d418d5bc02c8c64c9b04bae4fdd668b97e84226475d255af4456202de226ebbb50196ef
• Download URL:
  https://stacks.cdc.gov/view/cdc/214731/cdc_214731_DS1.pdf
• File Type:
  [PDF - 147.48 KB ]