The Effect of Vibration on Back Discomfort and Serum Levels of Von Willebrand Factor Antigen: A Preliminary Communication

Details

• Personal Author:
  Blann AD ; Jayson MIV ; Kaigle AM ; Pope MH ; Weinstein JN ; Wilder DG
• Description:
  The von Willebrand factor (vWf) is a complex protein whose release is a marker for endothelial damage; serum levels of its antigen (vWFAg) can be used as a marker for such changes. We measured the levels of back discomfort and vWFAg in 11 subjects following 25-min periods of (1) lying down, (2) sitting upright, (3) vibrating whilst sitting and (4) sitting upright. Back discomfort appeared and vWf levels were significantly increased following sitting upright, compared with lying flat, and increased further following vibration. They fell thereafter with a period of sitting still upright. These results demonstrate that vibration has a significant effect in increasing back discomfort and the serum levels of vWFAg, and it is possible that vibration may induce vascular damage within the spine. [Description provided by NIOSH]
• Subjects:
  Biomarkers Musculoskeletal System Occupational Health Safety Vibration
• Keywords:
  Author Keywords: Low Back Pain Back Pain Endothelium Spinal Cord Disorders Vascular Damage Vibration Effects Von Willebrand Factor Antigen
• ISSN:
  0940-6719
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Iowa ; OSHA Region 1 ; OSHA Region 7 ; Vermont
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  143-145
• Volume:
  3
• Issue:
  3
• NIOSHTIC Number:
  nn:20056721
• Citation:
  Eur Spine J 1994 Jun; 3(3):143-145
• Contact Point Address:
  M. H. Pope, Orthopaedics and Rehabilitation Department, University of Vermont, Burlington, VT 05405, USA
• Federal Fiscal Year:
  1994
• Performing Organization:
  University of Vermont & State Agriculture College, Burlington
• Peer Reviewed:
  True
• Start Date:
  19900701
• Source Full Name:
  European Spine Journal
• End Date:
  19940630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:80e9b4e5bc3f8cde6a0a03910d98ea90ffc304c167a3eaed056a522adf0650c278d119ed6591497b95a2129af11fe67e82d7c899088991182d7c0a7b8d920e87
• Download URL:
  https://stacks.cdc.gov/view/cdc/214273/cdc_214273_DS1.pdf
• File Type:
  [PDF - 782.40 KB ]